Entity Details

Primary name UCHL5_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9Y5K5
EntryNameUCHL5_HUMAN
FullNameUbiquitin carboxyl-terminal hydrolase isozyme L5
TaxID9606
Evidenceevidence at protein level
Length329
SequenceStatuscomplete
DateCreated2001-09-26
DateModified2021-06-02

Ontological Relatives

GenesUCHL5

GO terms

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GOName
GO:0000502 proteasome complex
GO:0003723 RNA binding
GO:0004843 thiol-dependent deubiquitinase
GO:0004866 endopeptidase inhibitor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006281 DNA repair
GO:0006310 DNA recombination
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0016579 protein deubiquitination
GO:0031011 Ino80 complex
GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0045880 positive regulation of smoothened signaling pathway
GO:0061136 regulation of proteasomal protein catabolic process
GO:0070628 proteasome binding

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR001578 Peptidase C12, ubiquitin carboxyl-terminal hydrolaseDomainDomain
IPR017390 Ubiquitinyl hydrolase, UCH37 typeFamilyFamily
IPR033837 Ubiquitinyl hydrolase-L5DomainDomain
IPR036959 Peptidase C12, ubiquitin carboxyl-terminal hydrolase superfamilyFamilyHomologous superfamily
IPR038765 Papain-like cysteine peptidase superfamilyFamilyHomologous superfamily
IPR041507 Peptidase C12, C-terminal domainDomainDomain

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
UCHL5_HUMANADRM1_MOUSEBioGRID25666615 details