Entity Details

Primary name MMP14_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP53690
EntryNameMMP14_MOUSE
FullNameMatrix metalloproteinase-14
TaxID10090
Evidenceevidence at transcript level
Length582
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesMmp14

GO terms

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GOName
GO:0001501 skeletal system development
GO:0001503 ossification
GO:0001525 angiogenesis
GO:0001541 ovarian follicle development
GO:0001666 response to hypoxia
GO:0001935 endothelial cell proliferation
GO:0001958 endochondral ossification
GO:0004175 endopeptidase activity
GO:0004222 metalloendopeptidase activity
GO:0005178 integrin binding
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006508 proteolysis
GO:0006979 response to oxidative stress
GO:0008270 zinc ion binding
GO:0008584 male gonad development
GO:0009612 response to mechanical stimulus
GO:0009725 response to hormone
GO:0010831 positive regulation of myotube differentiation
GO:0010954 positive regulation of protein processing
GO:0014070 response to organic cyclic compound
GO:0016021 integral component of membrane
GO:0016477 cell migration
GO:0030198 extracellular matrix organization
GO:0030307 positive regulation of cell growth
GO:0030324 lung development
GO:0030335 positive regulation of cell migration
GO:0030574 collagen catabolic process
GO:0031012 extracellular matrix
GO:0031410 cytoplasmic vesicle
GO:0031638 zymogen activation
GO:0035987 endodermal cell differentiation
GO:0035988 chondrocyte proliferation
GO:0042470 melanosome
GO:0043615 astrocyte cell migration
GO:0043627 response to estrogen
GO:0044354 macropinosome
GO:0045111 intermediate filament cytoskeleton
GO:0045579 positive regulation of B cell differentiation
GO:0045746 negative regulation of Notch signaling pathway
GO:0048701 embryonic cranial skeleton morphogenesis
GO:0048754 branching morphogenesis of an epithelial tube
GO:0048771 tissue remodeling
GO:0051895 negative regulation of focal adhesion assembly
GO:0060322 head development
GO:0060348 bone development
GO:0070006 metalloaminopeptidase activity
GO:0097094 craniofacial suture morphogenesis
GO:1903076 regulation of protein localization to plasma membrane
GO:1905523 positive regulation of macrophage migration
GO:1990834 response to odorant

Subcellular Location

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Subcellular Location
Cytoplasm
Melanosome
Membrane

Domains

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DomainNameCategoryType
IPR000585 Hemopexin-like domainDomainDomain
IPR001818 Peptidase M10, metallopeptidaseDomainDomain
IPR002477 Peptidoglycan binding-likeDomainDomain
IPR006026 Peptidase, metallopeptidaseDomainDomain
IPR018486 Hemopexin, conserved siteSiteConserved site
IPR018487 Hemopexin-like repeatsRepeatRepeat
IPR021158 Peptidase M10A, cysteine switch, zinc binding siteSiteBinding site
IPR021190 Peptidase M10AFamilyFamily
IPR021805 Peptidase M10A, matrix metallopeptidase, C-terminalDomainDomain
IPR024079 Metallopeptidase, catalytic domain superfamilyFamilyHomologous superfamily
IPR033739 Peptidase M10A, catalytic domainDomainDomain
IPR036365 PGBD-like superfamilyFamilyHomologous superfamily
IPR036366 PGBD superfamilyFamilyHomologous superfamily
IPR036375 Hemopexin-like domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
MMP14_MOUSEDLL1_MOUSEMINT21572390 details
MMP14_MOUSECAH9_HUMANBioGRID28692057 details