Entity Details

Primary name SESN1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9Y6P5
EntryNameSESN1_HUMAN
FullNameSestrin-1
TaxID9606
Evidenceevidence at protein level
Length492
SequenceStatuscomplete
DateCreated2001-04-27
DateModified2021-06-02

Ontological Relatives

GenesSESN1

GO terms

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GOName
GO:0001650 fibrillar center
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0016239 positive regulation of macroautophagy
GO:0016684 oxidoreductase activity, acting on peroxide as acceptor
GO:0034198 cellular response to amino acid starvation
GO:0042149 cellular response to glucose starvation
GO:0051920 peroxiredoxin activity
GO:0070728 leucine binding
GO:0071233 cellular response to leucine
GO:0072593 reactive oxygen species metabolic process
GO:0098869 cellular oxidant detoxification
GO:1901031 regulation of response to reactive oxygen species
GO:1904262 negative regulation of TORC1 signaling
GO:1990253 cellular response to leucine starvation

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR006730 SestrinFamilyFamily
IPR029032 AhpD-likeFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
SESN1_HUMANRBX1_MOUSEIntAct23274085 details