Entity Details

Primary name IDHP_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP54071
EntryNameIDHP_MOUSE
FullNameIsocitrate dehydrogenase [NADP], mitochondrial
TaxID10090
Evidenceevidence at protein level
Length452
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesIdh2

GO terms

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GOName
GO:0000287 magnesium ion binding
GO:0004448 isocitrate dehydrogenase activity
GO:0004450 isocitrate dehydrogenase (NADP+) activity
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005777 peroxisome
GO:0005829 cytosol
GO:0006097 glyoxylate cycle
GO:0006099 tricarboxylic acid cycle
GO:0006102 isocitrate metabolic process
GO:0006103 2-oxoglutarate metabolic process
GO:0006739 NADP metabolic process
GO:0006741 NADP biosynthetic process
GO:0051287 NAD binding
GO:0060253 negative regulation of glial cell proliferation
GO:1903976 negative regulation of glial cell migration
GO:1904465 negative regulation of matrix metallopeptidase secretion

Subcellular Location

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Subcellular Location
Mitochondrion

Domains

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DomainNameCategoryType
IPR004790 Isocitrate dehydrogenase NADP-dependentFamilyFamily
IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved siteSiteConserved site
IPR024084 Isopropylmalate dehydrogenase-like domainDomainDomain

Diseases

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Interactions

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InteractorPartnerSourcesPublicationsLink