Entity Details

Primary name EPHB4_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP54761
EntryNameEPHB4_MOUSE
FullNameEphrin type-B receptor 4
TaxID10090
Evidenceevidence at protein level
Length987
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesEphb4

GO terms

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GOName
GO:0001525 angiogenesis
GO:0002042 cell migration involved in sprouting angiogenesis
GO:0003007 heart morphogenesis
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0005003 ephrin receptor activity
GO:0005005 transmembrane-ephrin receptor activity
GO:0005524 ATP binding
GO:0005887 integral component of plasma membrane
GO:0007155 cell adhesion
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007275 multicellular organism development
GO:0007411 axon guidance
GO:0033674 positive regulation of kinase activity
GO:0043005 neuron projection
GO:0043235 receptor complex
GO:0046777 protein autophosphorylation
GO:0048013 ephrin receptor signaling pathway
GO:0048845 venous blood vessel morphogenesis
GO:1903849 positive regulation of aorta morphogenesis
GO:2000525 positive regulation of T cell costimulation

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000719 Protein kinase domainDomainDomain
IPR001090 Ephrin receptor ligand binding domainDomainDomain
IPR001245 Serine-threonine/tyrosine-protein kinase, catalytic domainDomainDomain
IPR001426 Tyrosine-protein kinase, receptor class V, conserved siteSiteConserved site
IPR001660 Sterile alpha motif domainDomainDomain
IPR003961 Fibronectin type IIIDomainDomain
IPR008266 Tyrosine-protein kinase, active siteSiteActive site
IPR008979 Galactose-binding-like domain superfamilyFamilyHomologous superfamily
IPR009030 Growth factor receptor cysteine-rich domain superfamilyFamilyHomologous superfamily
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR011641 Tyrosine-protein kinase ephrin type A/B receptor-likeDomainDomain
IPR013761 Sterile alpha motif/pointed domain superfamilyFamilyHomologous superfamily
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR016257 Ephrin receptor type-A /type-BFamilyFamily
IPR017441 Protein kinase, ATP binding siteSiteBinding site
IPR020635 Tyrosine-protein kinase, catalytic domainDomainDomain
IPR027936 Ephrin receptor, transmembrane domainDomainDomain
IPR034290 Ephrin type-B receptor 4, ligand binding domainDomainDomain
IPR036116 Fibronectin type III superfamilyFamilyHomologous superfamily
IPR037636 EPH-B4, SAM domainDomainDomain

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
EPHB4_MOUSEELF1_MOUSEBioGRID32325033 8954633 details
EPHB4_MOUSEELF2_MOUSEBioGRID8954633 details