Entity Details

Primary name EPHB2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP54763
EntryNameEPHB2_MOUSE
FullNameEphrin type-B receptor 2
TaxID10090
Evidenceevidence at protein level
Length986
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesEphb2

GO terms

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GOName
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0005654 nucleoplasm
GO:0005887 integral component of plasma membrane
GO:0006468 protein phosphorylation
GO:0007162 negative regulation of cell adhesion
GO:0007275 multicellular organism development
GO:0007413 axonal fasciculation
GO:0007611 learning or memory
GO:0007612 learning
GO:0009887 animal organ morphogenesis
GO:0038023 signaling receptor activity
GO:0042472 inner ear morphogenesis
GO:0048013 ephrin receptor signaling pathway
GO:0048170 positive regulation of long-term neuronal synaptic plasticity
GO:0060021 roof of mouth development
GO:0060997 dendritic spine morphogenesis
GO:0071679 commissural neuron axon guidance
GO:0001933 negative regulation of protein phosphorylation
GO:0004713 protein tyrosine kinase activity
GO:0005005 transmembrane-ephrin receptor activity
GO:0005524 ATP binding
GO:0005886 plasma membrane
GO:0008046 axon guidance receptor activity
GO:0018108 peptidyl-tyrosine phosphorylation
GO:0021631 optic nerve morphogenesis
GO:0030424 axon
GO:0031290 retinal ganglion cell axon guidance
GO:0032760 positive regulation of tumor necrosis factor production
GO:0043005 neuron projection
GO:0043235 receptor complex
GO:0044877 protein-containing complex binding
GO:0045202 synapse
GO:0048168 regulation of neuronal synaptic plasticity
GO:0050770 regulation of axonogenesis
GO:0050878 regulation of body fluid levels
GO:0098978 glutamatergic synapse
GO:0099055 integral component of postsynaptic membrane
GO:0106028 neuron projection retraction
GO:1904782 negative regulation of NMDA glutamate receptor activity
GO:1904783 positive regulation of NMDA glutamate receptor activity
GO:0001525 angiogenesis
GO:0005003 ephrin receptor activity
GO:0007411 axon guidance
GO:0010628 positive regulation of gene expression
GO:0016310 phosphorylation
GO:0022038 corpus callosum development
GO:0030335 positive regulation of cell migration
GO:0030890 positive regulation of B cell proliferation
GO:0031915 positive regulation of synaptic plasticity
GO:0033674 positive regulation of kinase activity
GO:0042802 identical protein binding
GO:0046580 negative regulation of Ras protein signal transduction
GO:0051963 regulation of synapse assembly
GO:0051965 positive regulation of synapse assembly
GO:0070373 negative regulation of ERK1 and ERK2 cascade
GO:0099056 integral component of presynaptic membrane
GO:1900273 positive regulation of long-term synaptic potentiation
GO:0000902 cell morphogenesis
GO:0001540 amyloid-beta binding
GO:0001655 urogenital system development
GO:0002639 positive regulation of immunoglobulin production
GO:0005102 signaling receptor binding
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
GO:0021952 central nervous system projection neuron axonogenesis
GO:0030193 regulation of blood coagulation
GO:0030425 dendrite
GO:0042113 B cell activation
GO:0043025 neuronal cell body
GO:0048593 camera-type eye morphogenesis
GO:0050771 negative regulation of axonogenesis
GO:0051389 obsolete inactivation of MAPKK activity
GO:0060996 dendritic spine development
GO:0097104 postsynaptic membrane assembly
GO:0099557 trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission
GO:1903078 positive regulation of protein localization to plasma membrane

Subcellular Location

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Subcellular Location
Cell membrane
Cell projection

Domains

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DomainNameCategoryType
IPR000719 Protein kinase domainDomainDomain
IPR001090 Ephrin receptor ligand binding domainDomainDomain
IPR001245 Serine-threonine/tyrosine-protein kinase, catalytic domainDomainDomain
IPR001426 Tyrosine-protein kinase, receptor class V, conserved siteSiteConserved site
IPR001660 Sterile alpha motif domainDomainDomain
IPR003961 Fibronectin type IIIDomainDomain
IPR008266 Tyrosine-protein kinase, active siteSiteActive site
IPR008979 Galactose-binding-like domain superfamilyFamilyHomologous superfamily
IPR009030 Growth factor receptor cysteine-rich domain superfamilyFamilyHomologous superfamily
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR011641 Tyrosine-protein kinase ephrin type A/B receptor-likeDomainDomain
IPR013761 Sterile alpha motif/pointed domain superfamilyFamilyHomologous superfamily
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR016257 Ephrin receptor type-A /type-BFamilyFamily
IPR017441 Protein kinase, ATP binding siteSiteBinding site
IPR020635 Tyrosine-protein kinase, catalytic domainDomainDomain
IPR027936 Ephrin receptor, transmembrane domainDomainDomain
IPR034238 Ephrin type-B receptor 2, ligand binding domainDomainDomain
IPR036116 Fibronectin type III superfamilyFamilyHomologous superfamily

Diseases

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