Entity Details

Primary name PUR8_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP54822
EntryNamePUR8_MOUSE
FullNameAdenylosuccinate lyase
TaxID10090
Evidenceevidence at protein level
Length484
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesAdsl

GO terms

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GOName
GO:0001666 response to hypoxia
GO:0004018 N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0006163 purine nucleotide metabolic process
GO:0006167 AMP biosynthetic process
GO:0006189 'de novo' IMP biosynthetic process
GO:0007584 response to nutrient
GO:0009060 aerobic respiration
GO:0009156 ribonucleoside monophosphate biosynthetic process
GO:0014850 response to muscle activity
GO:0032991 protein-containing complex
GO:0042594 response to starvation
GO:0042802 identical protein binding
GO:0044208 'de novo' AMP biosynthetic process
GO:0070626 (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity

Subcellular Location

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Domains

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DomainNameCategoryType
IPR000362 Fumarate lyase familyFamilyFamily
IPR004769 Adenylosuccinate lyaseFamilyFamily
IPR008948 L-Aspartase-likeFamilyHomologous superfamily
IPR019468 Adenylosuccinate lyase C-terminalDomainDomain
IPR020557 Fumarate lyase, conserved siteSiteConserved site
IPR022761 Fumarate lyase, N-terminalDomainDomain
IPR024083 Fumarase/histidase, N-terminalFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
PUR8_MOUSEITA2B_MOUSEBioGRID30333137 details