Entity Details

Primary name CATK_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP55097
EntryNameCATK_MOUSE
FullNameCathepsin K
TaxID10090
Evidenceevidence at protein level
Length329
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesCtsk

GO terms

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GOName
GO:0001957 intramembranous ossification
GO:0001968 fibronectin binding
GO:0004197 cysteine-type endopeptidase activity
GO:0005518 collagen binding
GO:0005615 extracellular space
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005764 lysosome
GO:0006590 thyroid hormone generation
GO:0006955 immune response
GO:0008234 cysteine-type peptidase activity
GO:0009897 external side of plasma membrane
GO:0016324 apical plasma membrane
GO:0030574 collagen catabolic process
GO:0043231 intracellular membrane-bounded organelle
GO:0043394 proteoglycan binding
GO:0045453 bone resorption
GO:0051603 proteolysis involved in cellular protein catabolic process
GO:0061037 negative regulation of cartilage development

Subcellular Location

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Subcellular Location
Apical cell membrane
Lysosome
Secreted

Domains

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DomainNameCategoryType
IPR000169 Cysteine peptidase, cysteine active siteSiteActive site
IPR000668 Peptidase C1A, papain C-terminalDomainDomain
IPR013201 Cathepsin propeptide inhibitor domain (I29)DomainDomain
IPR015644 Peptidase C1A, cathepsin KFamilyFamily
IPR025660 Cysteine peptidase, histidine active siteSiteActive site
IPR038765 Papain-like cysteine peptidase superfamilyFamilyHomologous superfamily
IPR039417 Papain-like cysteine endopeptidaseDomainDomain

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
CATK_MOUSEVGLU2_MOUSEMINT16957773 details