Entity Details

Primary name TYRO3_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP55144
EntryNameTYRO3_MOUSE
FullNameTyrosine-protein kinase receptor TYRO3
TaxID10090
Evidenceevidence at protein level
Length880
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesTyro3

GO terms

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GOName
GO:0001618 virus receptor activity
GO:0001779 natural killer cell differentiation
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005635 nuclear envelope
GO:0005789 endoplasmic reticulum membrane
GO:0005887 integral component of plasma membrane
GO:0006468 protein phosphorylation
GO:0006909 phagocytosis
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007218 neuropeptide signaling pathway
GO:0007275 multicellular organism development
GO:0007283 spermatogenesis
GO:0007399 nervous system development
GO:0009986 cell surface
GO:0016477 cell migration
GO:0021885 forebrain cell migration
GO:0030168 platelet activation
GO:0032940 secretion by cell
GO:0033674 positive regulation of kinase activity
GO:0034122 negative regulation of toll-like receptor signaling pathway
GO:0034446 substrate adhesion-dependent cell spreading
GO:0042698 ovulation cycle
GO:0043235 receptor complex
GO:0043277 apoptotic cell clearance
GO:0043491 protein kinase B signaling
GO:0043524 negative regulation of neuron apoptotic process
GO:0043548 phosphatidylinositol 3-kinase binding
GO:0045824 negative regulation of innate immune response
GO:0046777 protein autophosphorylation
GO:0050728 negative regulation of inflammatory response
GO:0051250 negative regulation of lymphocyte activation
GO:0060068 vagina development
GO:0070050 neuron cellular homeostasis
GO:0070527 platelet aggregation
GO:1903902 positive regulation of viral life cycle

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000719 Protein kinase domainDomainDomain
IPR001245 Serine-threonine/tyrosine-protein kinase, catalytic domainDomainDomain
IPR003598 Immunoglobulin subtype 2DomainDomain
IPR003599 Immunoglobulin subtypeDomainDomain
IPR003961 Fibronectin type IIIDomainDomain
IPR007110 Immunoglobulin-like domainDomainDomain
IPR008266 Tyrosine-protein kinase, active siteSiteActive site
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR013098 Immunoglobulin I-setDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR017441 Protein kinase, ATP binding siteSiteBinding site
IPR020635 Tyrosine-protein kinase, catalytic domainDomainDomain
IPR036116 Fibronectin type III superfamilyFamilyHomologous superfamily
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
TYRO3_MOUSEUFO_MOUSEBioGRID18787040 details