Entity Details

Primary name CADH5_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP55284
EntryNameCADH5_MOUSE
FullNameCadherin-5
TaxID10090
Evidenceevidence at protein level
Length784
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesCdh5

GO terms

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GOName
GO:0000902 cell morphogenesis
GO:0001932 regulation of protein phosphorylation
GO:0001944 vasculature development
GO:0001955 blood vessel maturation
GO:0005102 signaling receptor binding
GO:0005509 calcium ion binding
GO:0005654 nucleoplasm
GO:0005886 plasma membrane
GO:0005911 cell-cell junction
GO:0005912 adherens junction
GO:0005923 bicellular tight junction
GO:0006874 cellular calcium ion homeostasis
GO:0007043 cell-cell junction assembly
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
GO:0007179 transforming growth factor beta receptor signaling pathway
GO:0007275 multicellular organism development
GO:0008013 beta-catenin binding
GO:0008285 negative regulation of cell population proliferation
GO:0009897 external side of plasma membrane
GO:0009986 cell surface
GO:0010628 positive regulation of gene expression
GO:0016021 integral component of membrane
GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
GO:0016342 catenin complex
GO:0019903 protein phosphatase binding
GO:0030054 cell junction
GO:0030335 positive regulation of cell migration
GO:0030513 positive regulation of BMP signaling pathway
GO:0031115 negative regulation of microtubule polymerization
GO:0031334 positive regulation of protein-containing complex assembly
GO:0031965 nuclear membrane
GO:0034332 adherens junction organization
GO:0035307 positive regulation of protein dephosphorylation
GO:0043114 regulation of vascular permeability
GO:0043184 vascular endothelial growth factor receptor 2 binding
GO:0043534 blood vessel endothelial cell migration
GO:0044325 transmembrane transporter binding
GO:0044331 cell-cell adhesion mediated by cadherin
GO:0045296 cadherin binding
GO:0045766 positive regulation of angiogenesis
GO:0050728 negative regulation of inflammatory response
GO:0070051 fibrinogen binding
GO:0070700 BMP receptor binding
GO:0070830 bicellular tight junction assembly
GO:0071944 cell periphery
GO:0098609 cell-cell adhesion
GO:0098742 cell-cell adhesion via plasma-membrane adhesion molecules
GO:1902396 protein localization to bicellular tight junction
GO:1903142 positive regulation of establishment of endothelial barrier
GO:1990782 protein tyrosine kinase binding
GO:2000114 regulation of establishment of cell polarity
GO:2000352 negative regulation of endothelial cell apoptotic process

Subcellular Location

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Subcellular Location
Cell junction
Cell membrane

Domains

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DomainNameCategoryType
IPR000233 Cadherin, cytoplasmic domainDomainDomain
IPR002126 Cadherin-likeDomainDomain
IPR015919 Cadherin-like superfamilyFamilyHomologous superfamily
IPR020894 Cadherin conserved siteSiteConserved site
IPR027397 Catenin binding domain superfamilyFamilyHomologous superfamily
IPR030052 VE-cadherinFamilyFamily
IPR039808 CadherinFamilyFamily

Diseases

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