Entity Details

Primary name AQP2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP56402
EntryNameAQP2_MOUSE
FullNameAquaporin-2
TaxID10090
Evidenceevidence at protein level
Length271
SequenceStatuscomplete
DateCreated1998-07-15
DateModified2021-06-02

Ontological Relatives

GenesAqp2

GO terms

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GOName
GO:0003091 renal water homeostasis
GO:0003097 renal water transport
GO:0003779 actin binding
GO:0005372 water transmembrane transporter activity
GO:0005737 cytoplasm
GO:0005764 lysosome
GO:0005769 early endosome
GO:0005791 rough endoplasmic reticulum
GO:0005802 trans-Golgi network
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006833 water transport
GO:0006884 cell volume homeostasis
GO:0006915 apoptotic process
GO:0015168 glycerol transmembrane transporter activity
GO:0015250 water channel activity
GO:0015793 glycerol transport
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016323 basolateral plasma membrane
GO:0016324 apical plasma membrane
GO:0030042 actin filament depolymerization
GO:0030133 transport vesicle
GO:0030136 clathrin-coated vesicle
GO:0030165 PDZ domain binding
GO:0030659 cytoplasmic vesicle membrane
GO:0031303 integral component of endosome membrane
GO:0031410 cytoplasmic vesicle
GO:0032991 protein-containing complex
GO:0042631 cellular response to water deprivation
GO:0048471 perinuclear region of cytoplasm
GO:0051289 protein homotetramerization
GO:0051928 positive regulation of calcium ion transport
GO:0055037 recycling endosome
GO:0055038 recycling endosome membrane
GO:0070062 extracellular exosome
GO:0070382 exocytic vesicle
GO:0071280 cellular response to copper ion
GO:0071288 cellular response to mercury ion
GO:0072205 metanephric collecting duct development
GO:0098576 lumenal side of membrane

Subcellular Location

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Subcellular Location
Apical cell membrane
Basolateral cell membrane
Cell membrane
Cytoplasmic vesicle membrane
Golgi apparatus

Domains

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DomainNameCategoryType
IPR000425 Major intrinsic proteinFamilyFamily
IPR022357 Major intrinsic protein, conserved siteSiteConserved site
IPR023271 Aquaporin-likeFamilyHomologous superfamily
IPR034294 Aquaporin transporterFamilyFamily

Diseases

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Interactions

3 interactions