Entity Details

Primary name MC4R_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP56450
EntryNameMC4R_MOUSE
FullNameMelanocortin receptor 4
TaxID10090
Evidenceevidence at protein level
Length332
SequenceStatuscomplete
DateCreated1998-07-15
DateModified2021-06-02

Ontological Relatives

GenesMc4r

GO terms

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GOName
GO:0002024 diet induced thermogenesis
GO:0004930 G protein-coupled receptor activity
GO:0004977 melanocortin receptor activity
GO:0004980 melanocyte-stimulating hormone receptor activity
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0006112 energy reserve metabolic process
GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO:0007631 feeding behavior
GO:0016021 integral component of membrane
GO:0017046 peptide hormone binding
GO:0019222 regulation of metabolic process
GO:0030073 insulin secretion
GO:0031625 ubiquitin protein ligase binding
GO:0032868 response to insulin
GO:0042562 hormone binding
GO:0042923 neuropeptide binding
GO:0045780 positive regulation of bone resorption
GO:0060259 regulation of feeding behavior
GO:2000252 negative regulation of feeding behavior
GO:2000821 regulation of grooming behavior

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000155 Melanocortin 4 receptorFamilyFamily
IPR000276 G protein-coupled receptor, rhodopsin-likeFamilyFamily
IPR001671 Melanocortin/ACTH receptorFamilyFamily
IPR001908 Melanocortin receptorFamilyFamily
IPR017452 GPCR, rhodopsin-like, 7TMDomainDomain

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
MC4R_MOUSEATRN1_MOUSEBioGRID14531729 details
MC4R_MOUSEMSX1_MOUSEBioGRID9454589 details