Entity Details

Primary name EAA1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP56564
EntryNameEAA1_MOUSE
FullNameExcitatory amino acid transporter 1
TaxID10090
Evidenceevidence at protein level
Length543
SequenceStatuscomplete
DateCreated1998-12-15
DateModified2021-06-02

Ontological Relatives

GenesSlc1a3

GO terms

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GOName
GO:0005313 L-glutamate transmembrane transporter activity
GO:0005314 high-affinity glutamate transmembrane transporter activity
GO:0005743 mitochondrial inner membrane
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006883 cellular sodium ion homeostasis
GO:0007605 sensory perception of sound
GO:0009416 response to light stimulus
GO:0009449 gamma-aminobutyric acid biosynthetic process
GO:0009611 response to wounding
GO:0009925 basal plasma membrane
GO:0009986 cell surface
GO:0010035 response to inorganic substance
GO:0015172 acidic amino acid transmembrane transporter activity
GO:0015501 glutamate:sodium symporter activity
GO:0015813 L-glutamate transmembrane transport
GO:0016323 basolateral plasma membrane
GO:0016595 glutamate binding
GO:0016597 amino acid binding
GO:0021545 cranial nerve development
GO:0031223 auditory behavior
GO:0042493 response to drug
GO:0042995 cell projection
GO:0043005 neuron projection
GO:0043025 neuronal cell body
GO:0043197 dendritic spine
GO:0043200 response to amino acid
GO:0043490 malate-aspartate shuttle
GO:0045202 synapse
GO:0046677 response to antibiotic
GO:0046872 metal ion binding
GO:0048667 cell morphogenesis involved in neuron differentiation
GO:0050806 positive regulation of synaptic transmission
GO:0050885 neuromuscular process controlling balance
GO:0051938 L-glutamate import
GO:0070779 D-aspartate import across plasma membrane
GO:0071314 cellular response to cocaine
GO:0071805 potassium ion transmembrane transport
GO:0071944 cell periphery
GO:0098712 L-glutamate import across plasma membrane
GO:0098796 membrane protein complex
GO:0140009 L-aspartate import across plasma membrane
GO:1902476 chloride transmembrane transport

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR001991 Sodium:dicarboxylate symporterFamilyFamily
IPR018107 Sodium:dicarboxylate symporter, conserved siteSiteConserved site
IPR036458 Sodium:dicarboxylate symporter superfamilyFamilyHomologous superfamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
EAA1_MOUSESEPT4_MOUSEBioGRID14723703 details
EAA1_MOUSECQ047_MOUSEBioGRID14723703 details