Entity Details

Primary name EF2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP58252
EntryNameEF2_MOUSE
FullNameElongation factor 2
TaxID10090
Evidenceevidence at protein level
Length858
SequenceStatuscomplete
DateCreated2001-08-29
DateModified2021-06-02

Ontological Relatives

GenesEef2

GO terms

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GOName
GO:0002039 p53 binding
GO:0002244 hematopoietic progenitor cell differentiation
GO:0002931 response to ischemia
GO:0003009 skeletal muscle contraction
GO:0003723 RNA binding
GO:0003746 translation elongation factor activity
GO:0003924 GTPase activity
GO:0005525 GTP binding
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005844 polysome
GO:0005886 plasma membrane
GO:0006414 translational elongation
GO:0007568 aging
GO:0008097 5S rRNA binding
GO:0014009 glial cell proliferation
GO:0016235 aggresome
GO:0019901 protein kinase binding
GO:0032355 response to estradiol
GO:0034976 response to endoplasmic reticulum stress
GO:0035914 skeletal muscle cell differentiation
GO:0042493 response to drug
GO:0042542 response to hydrogen peroxide
GO:0042788 polysomal ribosome
GO:0043022 ribosome binding
GO:0045121 membrane raft
GO:0045202 synapse
GO:0045471 response to ethanol
GO:0045727 positive regulation of translation
GO:0051015 actin filament binding
GO:0051593 response to folic acid
GO:1990416 cellular response to brain-derived neurotrophic factor stimulus
GO:1990904 ribonucleoprotein complex
GO:2000767 positive regulation of cytoplasmic translation

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000640 Elongation factor EFG, domain V-likeDomainDomain
IPR000795 Translational (tr)-type GTP-binding domainDomainDomain
IPR004161 Translation elongation factor EFTu-like, domain 2DomainDomain
IPR005225 Small GTP-binding protein domainDomainDomain
IPR005517 Translation elongation factor EFG/EF2, domain IVDomainDomain
IPR009000 Translation protein, beta-barrel domain superfamilyFamilyHomologous superfamily
IPR014721 Ribosomal protein S5 domain 2-type fold, subgroupFamilyHomologous superfamily
IPR020568 Ribosomal protein S5 domain 2-type foldFamilyHomologous superfamily
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR031157 Tr-type G domain, conserved siteSiteConserved site
IPR035647 EF-G domain III/V-likeFamilyHomologous superfamily
IPR041095 Elongation Factor G, domain IIDomainDomain

Diseases

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Interactions

4 interactions