Entity Details

Primary name S12A3_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP59158
EntryNameS12A3_MOUSE
FullNameSolute carrier family 12 member 3
TaxID10090
Evidenceevidence at protein level
Length1002
SequenceStatuscomplete
DateCreated2002-12-13
DateModified2021-06-02

Ontological Relatives

GenesSlc12a3

GO terms

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GOName
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006814 sodium ion transport
GO:0006821 chloride transport
GO:0006884 cell volume homeostasis
GO:0008511 sodium:potassium:chloride symporter activity
GO:0015081 sodium ion transmembrane transporter activity
GO:0015378 sodium:chloride symporter activity
GO:0015379 potassium:chloride symporter activity
GO:0016021 integral component of membrane
GO:0016324 apical plasma membrane
GO:0019899 enzyme binding
GO:0031982 vesicle
GO:0035725 sodium ion transmembrane transport
GO:0055064 chloride ion homeostasis
GO:0055075 potassium ion homeostasis
GO:0055078 sodium ion homeostasis
GO:0070062 extracellular exosome
GO:1902476 chloride transmembrane transport
GO:1990573 potassium ion import across plasma membrane

Subcellular Location

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Subcellular Location
Apical cell membrane
Cell membrane

Domains

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DomainNameCategoryType
IPR002948 Thiazide-sensitive Na-K-Cl co-transporterFamilyFamily
IPR004841 Amino acid permease/ SLC12A domainDomainDomain
IPR004842 SLC12A transporter familyFamilyFamily
IPR013612 Amino acid permease, N-terminalDomainDomain
IPR018491 SLC12A transporter, C-terminalDomainDomain

Diseases

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Interactions

3 interactions