Entity Details

Primary name ASXL1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP59598
EntryNameASXL1_MOUSE
FullNamePolycomb group protein ASXL1
TaxID10090
Evidenceevidence at protein level
Length1514
SequenceStatuscomplete
DateCreated2003-04-23
DateModified2021-06-02

Ontological Relatives

GenesAsxl1

GO terms

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GOName
GO:0000902 cell morphogenesis
GO:0003007 heart morphogenesis
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003713 transcription coactivator activity
GO:0005634 nucleus
GO:0006351 transcription, DNA-templated
GO:0009887 animal organ morphogenesis
GO:0010888 negative regulation of lipid storage
GO:0030097 hemopoiesis
GO:0032526 response to retinoic acid
GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway
GO:0035517 PR-DUB complex
GO:0035522 monoubiquitinated histone H2A deubiquitination
GO:0035564 regulation of kidney size
GO:0042974 retinoic acid receptor binding
GO:0042975 peroxisome proliferator activated receptor binding
GO:0045599 negative regulation of fat cell differentiation
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046872 metal ion binding
GO:0048386 positive regulation of retinoic acid receptor signaling pathway
GO:0048534 hematopoietic or lymphoid organ development
GO:0048538 thymus development
GO:0048539 bone marrow development
GO:0048872 homeostasis of number of cells
GO:0060348 bone development
GO:0060430 lung saccule development
GO:0072015 glomerular visceral epithelial cell development

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR007759 ASXL, HARE-HTH domainDomainDomain
IPR024811 Polycomb protein ASX/ASX-likeFamilyFamily
IPR024815 ASX-like protein 1FamilyFamily
IPR026905 Protein ASX-like, PHD domainDomainDomain
IPR028020 ASX, DEUBAD domainDomainDomain

Diseases

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