Entity Details

Primary name NPL4_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP60670
EntryNameNPL4_MOUSE
FullNameNuclear protein localization protein 4 homolog
TaxID10090
Evidenceevidence at protein level
Length608
SequenceStatuscomplete
DateCreated2004-03-29
DateModified2021-06-02

Ontological Relatives

GenesNploc4

GO terms

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GOName
GO:0005634 nucleus
GO:0005783 endoplasmic reticulum
GO:0005829 cytosol
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0007030 Golgi organization
GO:0030433 ubiquitin-dependent ERAD pathway
GO:0030970 retrograde protein transport, ER to cytosol
GO:0031625 ubiquitin protein ligase binding
GO:0032480 negative regulation of type I interferon production
GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex
GO:0036501 UFD1-NPL4 complex
GO:0039536 negative regulation of RIG-I signaling pathway
GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network
GO:0043130 ubiquitin binding
GO:0044877 protein-containing complex binding
GO:0046872 metal ion binding
GO:0051117 ATPase binding

Subcellular Location

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Subcellular Location
Cytoplasm
Endoplasmic reticulum
Nucleus

Domains

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DomainNameCategoryType
IPR001876 Zinc finger, RanBP2-typeDomainDomain
IPR007716 NPL4, zinc-binding putativeDomainDomain
IPR007717 Nuclear pore localisation protein NPL4, C-terminalDomainDomain
IPR016563 Nuclear protein localization protein 4FamilyFamily
IPR024682 Nuclear pore localisation protein Npl4, ubiquitin-like domainDomainDomain
IPR029071 Ubiquitin-like domain superfamilyFamilyHomologous superfamily
IPR036443 Zinc finger, RanBP2-type superfamilyFamilyHomologous superfamily
IPR037518 MPN domainDomainDomain

Diseases

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Interactions

4 interactions