Entity Details

Primary name ACTB_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP60710
EntryNameACTB_MOUSE
FullNameActin, cytoplasmic 1
TaxID10090
Evidenceevidence at protein level
Length375
SequenceStatuscomplete
DateCreated1986-07-21
DateModified2021-06-02

Ontological Relatives

GenesActb

GO terms

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GOName
GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0001725 stress fiber
GO:0001738 morphogenesis of a polarized epithelium
GO:0002102 podosome
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0005884 actin filament
GO:0005886 plasma membrane
GO:0005911 cell-cell junction
GO:0005912 adherens junction
GO:0005925 focal adhesion
GO:0007163 establishment or maintenance of cell polarity
GO:0007409 axonogenesis
GO:0014069 postsynaptic density
GO:0015629 actin cytoskeleton
GO:0016020 membrane
GO:0019894 kinesin binding
GO:0019901 protein kinase binding
GO:0022898 regulation of transmembrane transporter activity
GO:0030027 lamellipodium
GO:0030424 axon
GO:0030863 cortical cytoskeleton
GO:0030957 Tat protein binding
GO:0032091 negative regulation of protein binding
GO:0032991 protein-containing complex
GO:0034333 adherens junction assembly
GO:0035267 NuA4 histone acetyltransferase complex
GO:0036464 cytoplasmic ribonucleoprotein granule
GO:0042802 identical protein binding
GO:0043209 myelin sheath
GO:0043296 apical junction complex
GO:0044305 calyx of Held
GO:0045121 membrane raft
GO:0045176 apical protein localization
GO:0045202 synapse
GO:0048488 synaptic vesicle endocytosis
GO:0048870 cell motility
GO:0050998 nitric-oxide synthase binding
GO:0051621 regulation of norepinephrine uptake
GO:0070160 tight junction
GO:0071257 cellular response to electrical stimulus
GO:0071896 protein localization to adherens junction
GO:0072749 cellular response to cytochalasin B
GO:0097433 dense body
GO:0098685 Schaffer collateral - CA1 synapse
GO:0098871 postsynaptic actin cytoskeleton
GO:0098973 structural constituent of postsynaptic actin cytoskeleton
GO:0098974 postsynaptic actin cytoskeleton organization
GO:0098978 glutamatergic synapse
GO:0150111 regulation of transepithelial transport
GO:1903076 regulation of protein localization to plasma membrane
GO:1904030 negative regulation of cyclin-dependent protein kinase activity
GO:1990904 ribonucleoprotein complex

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR004000 Actin familyFamilyFamily
IPR004001 Actin, conserved siteSiteConserved site
IPR020902 Actin/actin-like conserved siteSiteConserved site
IPR043129 ATPase, nucleotide binding domainFamilyHomologous superfamily

Diseases

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Interactions

31 interactions

InteractorPartnerSourcesPublicationsLink
ACTB_MOUSEKPCE_MOUSEBioGRID, MINT15251432 32325033 details
ACTB_MOUSECXAR_MOUSEMINT17531226 details
ACTB_MOUSEPROF2_MOUSEBioGRID, MINT11034907 17541406 32325033 9463375 details
ACTB_MOUSEPKHH2_MOUSEUniProt22832517 details
ACTB_MOUSECPNE1_HUMANBioGRID12522145 details
ACTB_MOUSECPNE2_HUMANBioGRID12522145 details
ACTB_MOUSECPNE4_HUMANBioGRID12522145 details
ACTB_MOUSECOTL1_MOUSEBioGRID11785969 32325033 details
ACTB_MOUSETRPM7_MOUSEIntAct, MINT16407977 24855944 details
ACTB_MOUSESEPT2_MOUSEMINT17024187 details
ACTB_MOUSEPROF1_MOUSEBioGRID, MINT17541406 32325033 9463375 details
ACTB_MOUSEPKD1_MOUSEMINT17707375 details
ACTB_MOUSECAV1_MOUSEIntAct15293782 details
ACTB_MOUSEKAT5_MOUSEBioGRID, IntAct20946988 24302573 details
ACTB_MOUSEPROM1_HUMANUniProt18654668 details
ACTB_MOUSEPKNX1_MOUSEBioGRID17623278 details
ACTB_MOUSETRAF6_MOUSEBioGRID16196101 details
ACTB_MOUSEVATA_MOUSEBioGRID16196101 32325033 details
ACTB_MOUSESET_MOUSEBioGRID17309103 details
ACTB_MOUSEDMRT2_MOUSEBioGRID20975687 details
ACTB_MOUSEPROM1_MOUSEBioGRID18654668 details
ACTB_MOUSEFBX32_MOUSEBioGRID22673621 details
ACTB_MOUSERARA_MOUSEBioGRID18495661 details
ACTB_MOUSENEP_MOUSEBioGRID15944124 details
ACTB_MOUSEPRKN_MOUSEBioGRID24879156 details
ACTB_MOUSEMT3_MOUSEBioGRID15802640 17018872 details
ACTB_MOUSEINADL_MOUSEBioGRID19138174 details
ACTB_MOUSENEB2_MOUSEBioGRID28634551 30562941 details
ACTB_MOUSEDAB1_MOUSEBioGRID15110774 details
ACTB_MOUSEMYH9_MOUSEBioGRID29956586 31189591 32325033 details
ACTB_MOUSEIF2B1_MOUSEBioGRID31189591 details