Entity Details

Primary name NFX1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionB1AY10
EntryNameNFX1_MOUSE
FullNameTranscriptional repressor NF-X1
TaxID10090
Evidenceevidence at protein level
Length1114
SequenceStatuscomplete
DateCreated2008-05-20
DateModified2021-06-02

Ontological Relatives

GenesNfx1

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006355 regulation of transcription, DNA-templated
GO:0008270 zinc ion binding
GO:0045347 negative regulation of MHC class II biosynthetic process
GO:0051865 protein autoubiquitination
GO:0061630 ubiquitin protein ligase activity

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR000967 Zinc finger, NF-X1-typeDomainDomain
IPR001374 R3H domainDomainDomain
IPR001841 Zinc finger, RING-typeDomainDomain
IPR019786 Zinc finger, PHD-type, conserved siteSiteConserved site
IPR019787 Zinc finger, PHD-fingerDomainDomain
IPR034076 Transcriptional repressor NF-X1, R3H domainDomainDomain
IPR034078 Transcription factor NFX1 familyFamilyFamily
IPR036867 R3H domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
NFX1_MOUSENECD_MOUSEBioGRID22442722 details
NFX1_MOUSEUSP9X_HUMANBioGRID31059266 details