Entity Details

Primary name PPLA_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP61014
EntryNamePPLA_MOUSE
FullNameCardiac phospholamban
TaxID10090
Evidenceevidence at protein level
Length52
SequenceStatuscomplete
DateCreated2004-04-26
DateModified2021-06-02

Ontological Relatives

GenesPln

GO terms

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GOName
GO:0002026 regulation of the force of heart contraction
GO:0005789 endoplasmic reticulum membrane
GO:0006816 calcium ion transport
GO:0006874 cellular calcium ion homeostasis
GO:0007219 Notch signaling pathway
GO:0008016 regulation of heart contraction
GO:0010043 response to zinc ion
GO:0010459 negative regulation of heart rate
GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
GO:0010881 regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
GO:0016529 sarcoplasmic reticulum
GO:0031966 mitochondrial membrane
GO:0031982 vesicle
GO:0032868 response to insulin
GO:0032991 protein-containing complex
GO:0033017 sarcoplasmic reticulum membrane
GO:0033574 response to testosterone
GO:0042030 ATPase inhibitor activity
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0045822 negative regulation of heart contraction
GO:0048738 cardiac muscle tissue development
GO:0051924 regulation of calcium ion transport
GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity
GO:0086004 regulation of cardiac muscle cell contraction
GO:0086023 adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process
GO:0086092 regulation of the force of heart contraction by cardiac conduction
GO:0090279 regulation of calcium ion import
GO:0090534 calcium ion-transporting ATPase complex
GO:1901077 regulation of relaxation of muscle
GO:1901877 negative regulation of calcium ion binding
GO:1901895 negative regulation of ATPase-coupled calcium transmembrane transporter activity
GO:1902081 negative regulation of calcium ion import into sarcoplasmic reticulum

Subcellular Location

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Subcellular Location
Endoplasmic reticulum membrane
Membrane
Mitochondrion membrane
Sarcoplasmic reticulum membrane

Domains

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DomainNameCategoryType
IPR005984 PhospholambanFamilyFamily

Diseases

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Interactions

4 interactions