Entity Details

Primary name LHX5_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP61375
EntryNameLHX5_MOUSE
FullNameLIM/homeobox protein Lhx5
TaxID10090
Evidenceevidence at transcript level
Length402
SequenceStatuscomplete
DateCreated2004-05-24
DateModified2021-06-02

Ontological Relatives

GenesLhx5

GO terms

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GOName
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0005634 nucleus
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007267 cell-cell signaling
GO:0021527 spinal cord association neuron differentiation
GO:0021549 cerebellum development
GO:0021702 cerebellar Purkinje cell differentiation
GO:0021766 hippocampus development
GO:0021846 cell proliferation in forebrain
GO:0021879 forebrain neuron differentiation
GO:0021937 cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation
GO:0030182 neuron differentiation
GO:0042127 regulation of cell population proliferation
GO:0045893 positive regulation of transcription, DNA-templated
GO:0046872 metal ion binding
GO:1990837 sequence-specific double-stranded DNA binding

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR001356 Homeobox domainDomainDomain
IPR001781 Zinc finger, LIM-typeDomainDomain
IPR009057 Homeobox-like domain superfamilyFamilyHomologous superfamily
IPR017970 Homeobox, conserved siteSiteConserved site

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
LHX5_MOUSELDB1_MOUSEBioGRID, IntAct20211142 details
LHX5_MOUSELDB2_MOUSEBioGRID, IntAct20211142 details