Entity Details

Primary name PRS8_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP62196
EntryNamePRS8_MOUSE
FullName26S proteasome regulatory subunit 8
TaxID10090
Evidenceevidence at protein level
Length406
SequenceStatuscomplete
DateCreated2004-06-21
DateModified2021-06-02

Ontological Relatives

GenesPsmc5

GO terms

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GOName
GO:0000502 proteasome complex
GO:0005102 signaling receptor binding
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005675 transcription factor TFIIH holo complex
GO:0005737 cytoplasm
GO:0005838 proteasome regulatory particle
GO:0006357 regulation of transcription by RNA polymerase II
GO:0008134 transcription factor binding
GO:0008540 proteasome regulatory particle, base subcomplex
GO:0016234 inclusion body
GO:0016887 ATP hydrolysis activity
GO:0017025 TBP-class protein binding
GO:0022624 proteasome accessory complex
GO:0031410 cytoplasmic vesicle
GO:0031531 thyrotropin-releasing hormone receptor binding
GO:0031595 nuclear proteasome complex
GO:0031597 cytosolic proteasome complex
GO:0036402 proteasome-activating activity
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045899 positive regulation of RNA polymerase II transcription preinitiation complex assembly
GO:0050804 modulation of chemical synaptic transmission
GO:0090261 positive regulation of inclusion body assembly
GO:0098794 postsynapse

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR003593 AAA+ ATPase domainDomainDomain
IPR003959 ATPase, AAA-type, coreDomainDomain
IPR003960 ATPase, AAA-type, conserved siteSiteConserved site
IPR005937 26S proteasome regulatory subunit P45-likeFamilyFamily
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR032501 Proteasomal ATPase OB C-terminal domainDomainDomain
IPR041569 AAA ATPase, AAA+ lid domainDomainDomain

Diseases

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