Entity Details

Primary name PROF1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP62962
EntryNamePROF1_MOUSE
FullNameProfilin-1
TaxID10090
Evidenceevidence at protein level
Length140
SequenceStatuscomplete
DateCreated2004-08-31
DateModified2021-06-02

Ontological Relatives

GenesPfn1

GO terms

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GOName
GO:0000774 adenyl-nucleotide exchange factor activity
GO:0001784 phosphotyrosine residue binding
GO:0001843 neural tube closure
GO:0003779 actin binding
GO:0003785 actin monomer binding
GO:0005102 signaling receptor binding
GO:0005546 phosphatidylinositol-4,5-bisphosphate binding
GO:0005576 extracellular region
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0005938 cell cortex
GO:0006357 regulation of transcription by RNA polymerase II
GO:0008064 regulation of actin polymerization or depolymerization
GO:0010634 positive regulation of epithelial cell migration
GO:0030036 actin cytoskeleton organization
GO:0030833 regulation of actin filament polymerization
GO:0030837 negative regulation of actin filament polymerization
GO:0030838 positive regulation of actin filament polymerization
GO:0031267 small GTPase binding
GO:0032232 negative regulation of actin filament bundle assembly
GO:0032233 positive regulation of actin filament bundle assembly
GO:0032781 positive regulation of ATPase activity
GO:0042989 sequestering of actin monomers
GO:0043005 neuron projection
GO:0045202 synapse
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0050434 positive regulation of viral transcription
GO:0050821 protein stabilization
GO:0051054 positive regulation of DNA metabolic process
GO:0051496 positive regulation of stress fiber assembly
GO:0051497 negative regulation of stress fiber assembly
GO:0060074 synapse maturation
GO:0070064 proline-rich region binding
GO:0071363 cellular response to growth factor stimulus
GO:0098685 Schaffer collateral - CA1 synapse
GO:0098688 parallel fiber to Purkinje cell synapse
GO:0098793 presynapse
GO:0098794 postsynapse
GO:0098885 modification of postsynaptic actin cytoskeleton
GO:0098978 glutamatergic synapse
GO:1900029 positive regulation of ruffle assembly

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR005454 Profilin1/2/3, vertebrateFamilyFamily
IPR005455 ProfilinFamilyFamily
IPR027310 Profilin conserved siteSiteConserved site
IPR029892 Profilin-1FamilyFamily
IPR036140 Profilin superfamilyFamilyHomologous superfamily

Diseases

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