Entity Details

Primary name LIS1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP63005
EntryNameLIS1_MOUSE
FullNamePlatelet-activating factor acetylhydrolase IB subunit beta
TaxID10090
Evidenceevidence at protein level
Length410
SequenceStatuscomplete
DateCreated2004-08-31
DateModified2021-06-02

Ontological Relatives

GenesPafah1b1

GO terms

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GOName
GO:0000132 establishment of mitotic spindle orientation
GO:0000226 microtubule cytoskeleton organization
GO:0000235 astral microtubule
GO:0000776 kinetochore
GO:0001667 ameboidal-type cell migration
GO:0001675 acrosome assembly
GO:0001764 neuron migration
GO:0001961 positive regulation of cytokine-mediated signaling pathway
GO:0005635 nuclear envelope
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005829 cytosol
GO:0005871 kinesin complex
GO:0005875 microtubule associated complex
GO:0005881 cytoplasmic microtubule
GO:0005938 cell cortex
GO:0007017 microtubule-based process
GO:0007097 nuclear migration
GO:0007268 chemical synaptic transmission
GO:0007281 germ cell development
GO:0007405 neuroblast proliferation
GO:0007611 learning or memory
GO:0008017 microtubule binding
GO:0008090 retrograde axonal transport
GO:0008247 1-alkyl-2-acetylglycerophosphocholine esterase complex
GO:0008344 adult locomotory behavior
GO:0009306 protein secretion
GO:0010977 negative regulation of neuron projection development
GO:0015630 microtubule cytoskeleton
GO:0016042 lipid catabolic process
GO:0016477 cell migration
GO:0017145 stem cell division
GO:0019226 transmission of nerve impulse
GO:0021540 corpus callosum morphogenesis
GO:0021766 hippocampus development
GO:0021819 layer formation in cerebral cortex
GO:0021895 cerebral cortex neuron differentiation
GO:0021987 cerebral cortex development
GO:0030036 actin cytoskeleton organization
GO:0030424 axon
GO:0030426 growth cone
GO:0031023 microtubule organizing center organization
GO:0031252 cell leading edge
GO:0031514 motile cilium
GO:0031965 nuclear membrane
GO:0031982 vesicle
GO:0032420 stereocilium
GO:0036035 osteoclast development
GO:0038026 reelin-mediated signaling pathway
GO:0040019 positive regulation of embryonic development
GO:0042249 establishment of planar polarity of embryonic epithelium
GO:0042802 identical protein binding
GO:0043005 neuron projection
GO:0043025 neuronal cell body
GO:0043087 regulation of GTPase activity
GO:0043622 cortical microtubule organization
GO:0044877 protein-containing complex binding
GO:0045202 synapse
GO:0045505 dynein intermediate chain binding
GO:0045773 positive regulation of axon extension
GO:0045931 positive regulation of mitotic cell cycle
GO:0046329 negative regulation of JNK cascade
GO:0046982 protein heterodimerization activity
GO:0047496 vesicle transport along microtubule
GO:0048471 perinuclear region of cytoplasm
GO:0048854 brain morphogenesis
GO:0050885 neuromuscular process controlling balance
GO:0051010 microtubule plus-end binding
GO:0051012 microtubule sliding
GO:0051081 nuclear membrane disassembly
GO:0051130 positive regulation of cellular component organization
GO:0051219 phosphoprotein binding
GO:0051660 establishment of centrosome localization
GO:0051661 maintenance of centrosome location
GO:0060117 auditory receptor cell development
GO:0061003 positive regulation of dendritic spine morphogenesis
GO:0070507 regulation of microtubule cytoskeleton organization
GO:0070840 dynein complex binding
GO:0090102 cochlea development
GO:0090176 microtubule cytoskeleton organization involved in establishment of planar polarity
GO:0090724 central region of growth cone
GO:1904115 axon cytoplasm
GO:2000574 obsolete regulation of microtubule motor activity

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus membrane

Domains

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DomainNameCategoryType
IPR001680 WD40 repeatRepeatRepeat
IPR006594 LIS1 homology motifDomainDomain
IPR015943 WD40/YVTN repeat-like-containing domain superfamilyFamilyHomologous superfamily
IPR017252 Dynein regulator LIS1FamilyFamily
IPR019775 WD40 repeat, conserved siteSiteConserved site
IPR020472 G-protein beta WD-40 repeatRepeatRepeat
IPR036322 WD40-repeat-containing domain superfamilyFamilyHomologous superfamily
IPR037190 LIS1, N-terminalFamilyHomologous superfamily

Diseases

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