Entity Details

Primary name CH60_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP63038
EntryNameCH60_MOUSE
FullName60 kDa heat shock protein, mitochondrial
TaxID10090
Evidenceevidence at protein level
Length573
SequenceStatuscomplete
DateCreated2004-08-31
DateModified2021-06-02

Ontological Relatives

GenesHspd1

GO terms

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GOName
GO:0001530 lipopolysaccharide binding
GO:0001666 response to hypoxia
GO:0002039 p53 binding
GO:0002755 MyD88-dependent toll-like receptor signaling pathway
GO:0002842 positive regulation of T cell mediated immune response to tumor cell
GO:0002931 response to ischemia
GO:0003725 double-stranded RNA binding
GO:0005524 ATP binding
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005759 mitochondrial matrix
GO:0005769 early endosome
GO:0005782 peroxisomal matrix
GO:0005791 rough endoplasmic reticulum
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005905 clathrin-coated pit
GO:0006457 protein folding
GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0006986 response to unfolded protein
GO:0008035 high-density lipoprotein particle binding
GO:0008637 apoptotic mitochondrial changes
GO:0009409 response to cold
GO:0009986 cell surface
GO:0014823 response to activity
GO:0016020 membrane
GO:0016853 isomerase activity
GO:0016887 ATP hydrolysis activity
GO:0019899 enzyme binding
GO:0030061 mitochondrial crista
GO:0030135 coated vesicle
GO:0030141 secretory granule
GO:0031625 ubiquitin protein ligase binding
GO:0031985 Golgi cisterna
GO:0032496 response to lipopolysaccharide
GO:0032727 positive regulation of interferon-alpha production
GO:0032729 positive regulation of interferon-gamma production
GO:0032733 positive regulation of interleukin-10 production
GO:0032735 positive regulation of interleukin-12 production
GO:0032755 positive regulation of interleukin-6 production
GO:0032760 positive regulation of tumor necrosis factor production
GO:0032991 protein-containing complex
GO:0033198 response to ATP
GO:0034185 apolipoprotein binding
GO:0034186 apolipoprotein A-I binding
GO:0034514 mitochondrial unfolded protein response
GO:0034605 cellular response to heat
GO:0042026 protein refolding
GO:0042100 B cell proliferation
GO:0042110 T cell activation
GO:0042113 B cell activation
GO:0042220 response to cocaine
GO:0042493 response to drug
GO:0042542 response to hydrogen peroxide
GO:0042588 zymogen granule
GO:0043032 positive regulation of macrophage activation
GO:0043065 positive regulation of apoptotic process
GO:0043066 negative regulation of apoptotic process
GO:0043209 myelin sheath
GO:0043231 intracellular membrane-bounded organelle
GO:0043524 negative regulation of neuron apoptotic process
GO:0043627 response to estrogen
GO:0044877 protein-containing complex binding
GO:0045041 protein import into mitochondrial intermembrane space
GO:0045121 membrane raft
GO:0046696 lipopolysaccharide receptor complex
GO:0048291 isotype switching to IgG isotypes
GO:0050729 positive regulation of inflammatory response
GO:0050821 protein stabilization
GO:0050870 positive regulation of T cell activation
GO:0051087 chaperone binding
GO:0051384 response to glucocorticoid
GO:0051702 biological process involved in interaction with symbiont
GO:0070062 extracellular exosome
GO:0071866 negative regulation of apoptotic process in bone marrow cell
GO:0098761 cellular response to interleukin-7
GO:0140030 modification-dependent protein binding
GO:1903427 negative regulation of reactive oxygen species biosynthetic process

Subcellular Location

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Subcellular Location
Mitochondrion matrix

Domains

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DomainNameCategoryType
IPR001844 Chaperonin Cpn60FamilyFamily
IPR002423 Chaperonin Cpn60/TCP-1 familyFamilyFamily
IPR018370 Chaperonin Cpn60, conserved siteSiteConserved site
IPR027409 GroEL-like apical domain superfamilyFamilyHomologous superfamily
IPR027410 TCP-1-like chaperonin intermediate domain superfamilyFamilyHomologous superfamily
IPR027413 GroEL-like equatorial domain superfamilyFamilyHomologous superfamily

Diseases

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