Entity Details

Primary name GBRB3_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP63080
EntryNameGBRB3_MOUSE
FullNameGamma-aminobutyric acid receptor subunit beta-3
TaxID10090
Evidenceevidence at protein level
Length473
SequenceStatuscomplete
DateCreated2004-09-13
DateModified2021-06-02

Ontological Relatives

GenesGabrb3

GO terms

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GOName
GO:0004890 GABA-A receptor activity
GO:0005216 ion channel activity
GO:0005254 chloride channel activity
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0007165 signal transduction
GO:0007214 gamma-aminobutyric acid signaling pathway
GO:0007268 chemical synaptic transmission
GO:0007399 nervous system development
GO:0007420 brain development
GO:0007605 sensory perception of sound
GO:0007612 learning
GO:0007613 memory
GO:0009986 cell surface
GO:0019098 reproductive behavior
GO:0021549 cerebellum development
GO:0022851 GABA-gated chloride ion channel activity
GO:0030594 neurotransmitter receptor activity
GO:0030659 cytoplasmic vesicle membrane
GO:0034220 ion transmembrane transport
GO:0034707 chloride channel complex
GO:0035176 social behavior
GO:0035612 AP-2 adaptor complex binding
GO:0035640 exploration behavior
GO:0042391 regulation of membrane potential
GO:0042493 response to drug
GO:0042747 circadian sleep/wake cycle, REM sleep
GO:0042802 identical protein binding
GO:0043005 neuron projection
GO:0043195 terminal bouton
GO:0043523 regulation of neuron apoptotic process
GO:0043524 negative regulation of neuron apoptotic process
GO:0045202 synapse
GO:0048666 neuron development
GO:0050877 nervous system process
GO:0051932 synaptic transmission, GABAergic
GO:0060021 roof of mouth development
GO:0060022 hard palate development
GO:0060077 inhibitory synapse
GO:0060080 inhibitory postsynaptic potential
GO:0060119 inner ear receptor cell development
GO:0060384 innervation
GO:0061744 motor behavior
GO:0071294 cellular response to zinc ion
GO:0071420 cellular response to histamine
GO:0072347 response to anesthetic
GO:0090102 cochlea development
GO:0098982 GABA-ergic synapse
GO:0099055 integral component of postsynaptic membrane
GO:0099060 integral component of postsynaptic specialization membrane
GO:1901215 negative regulation of neuron death
GO:1902476 chloride transmembrane transport
GO:1902711 GABA-A receptor complex
GO:1904315 transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential
GO:1904862 inhibitory synapse assembly

Subcellular Location

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Subcellular Location
Cell junction
Cell membrane
Cytoplasmic vesicle membrane

Domains

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DomainNameCategoryType
IPR002289 Gamma-aminobutyric-acid A receptor, beta subunitFamilyFamily
IPR006028 Gamma-aminobutyric acid A receptor/Glycine receptor alphaFamilyFamily
IPR006029 Neurotransmitter-gated ion-channel transmembrane domainDomainDomain
IPR006201 Neurotransmitter-gated ion-channelFamilyFamily
IPR006202 Neurotransmitter-gated ion-channel ligand-binding domainDomainDomain
IPR018000 Neurotransmitter-gated ion-channel, conserved siteSiteConserved site
IPR036719 Neurotransmitter-gated ion-channel transmembrane domain superfamilyFamilyHomologous superfamily
IPR036734 Neurotransmitter-gated ion-channel ligand-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
GBRB3_MOUSEOTUD4_HUMANBioGRID31138677 details
GBRB3_MOUSEGBRA1_MOUSEBioGRID22768092 details