Entity Details

Primary name PYR1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionB2RQC6
EntryNamePYR1_MOUSE
FullNameCAD protein
TaxID10090
Evidenceevidence at protein level
Length2225
SequenceStatuscomplete
DateCreated2014-03-19
DateModified2021-06-02

Ontological Relatives

GenesCad

GO terms

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GOName
GO:0001889 liver development
GO:0002134 UTP binding
GO:0004070 aspartate carbamoyltransferase activity
GO:0004088 carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GO:0004151 dihydroorotase activity
GO:0004672 protein kinase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process
GO:0006228 UTP biosynthetic process
GO:0006541 glutamine metabolic process
GO:0006807 nitrogen compound metabolic process
GO:0007507 heart development
GO:0007565 female pregnancy
GO:0007595 lactation
GO:0008270 zinc ion binding
GO:0014075 response to amine
GO:0016363 nuclear matrix
GO:0016597 amino acid binding
GO:0017144 drug metabolic process
GO:0018107 peptidyl-threonine phosphorylation
GO:0019240 citrulline biosynthetic process
GO:0019899 enzyme binding
GO:0031000 response to caffeine
GO:0031100 animal organ regeneration
GO:0032868 response to insulin
GO:0032991 protein-containing complex
GO:0033574 response to testosterone
GO:0035690 cellular response to drug
GO:0042594 response to starvation
GO:0042802 identical protein binding
GO:0042995 cell projection
GO:0043025 neuronal cell body
GO:0043195 terminal bouton
GO:0044205 'de novo' UMP biosynthetic process
GO:0046777 protein autophosphorylation
GO:0051414 response to cortisol
GO:0071364 cellular response to epidermal growth factor stimulus

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR002082 Aspartate carbamoyltransferaseFamilyFamily
IPR002195 Dihydroorotase, conserved siteSiteConserved site
IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domainDomainDomain
IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domainDomainDomain
IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domainDomainDomain
IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domainDomainDomain
IPR006130 Aspartate/ornithine carbamoyltransferaseFamilyFamily
IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domainDomainDomain
IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P bindingDomainDomain
IPR006274 Carbamoyl-phosphate synthase, small subunitFamilyFamily
IPR006275 Carbamoyl-phosphate synthase, large subunitFamilyFamily
IPR006680 Amidohydrolase-relatedDomainDomain
IPR011059 Metal-dependent hydrolase, composite domain superfamilyFamilyHomologous superfamily
IPR011607 Methylglyoxal synthase-like domainDomainDomain
IPR011761 ATP-grasp foldDomainDomain
IPR013815 ATP-grasp fold, subdomain 1FamilyHomologous superfamily
IPR016185 Pre-ATP-grasp domain superfamilyFamilyHomologous superfamily
IPR017926 Glutamine amidotransferaseDomainDomain
IPR029062 Class I glutamine amidotransferase-likeFamilyHomologous superfamily
IPR032466 Metal-dependent hydrolaseFamilyHomologous superfamily
IPR035686 Carbamoyl-phosphate synthase small subunit, GATase1 domainDomainDomain
IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamilyFamilyHomologous superfamily
IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamilyFamilyHomologous superfamily
IPR036901 Aspartate/ornithine carbamoyltransferase superfamilyFamilyHomologous superfamily
IPR036914 Methylglyoxal synthase-like domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
PYR1_MOUSEKS6B1_HUMANDIP23429703 details