Entity Details

Primary name PP2AA_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP63330
EntryNamePP2AA_MOUSE
FullNameSerine/threonine-protein phosphatase 2A catalytic subunit alpha isoform
TaxID10090
Evidenceevidence at protein level
Length309
SequenceStatuscomplete
DateCreated2004-10-11
DateModified2021-06-02

Ontological Relatives

GenesPpp2ca

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000159 protein phosphatase type 2A complex
GO:0000775 chromosome, centromeric region
GO:0000922 spindle pole
GO:0001932 regulation of protein phosphorylation
GO:0001933 negative regulation of protein phosphorylation
GO:0004722 protein serine/threonine phosphatase activity
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006470 protein dephosphorylation
GO:0007498 mesoderm development
GO:0008022 protein C-terminus binding
GO:0010288 response to lead ion
GO:0010469 regulation of signaling receptor activity
GO:0010719 negative regulation of epithelial to mesenchymal transition
GO:0014069 postsynaptic density
GO:0019899 enzyme binding
GO:0019901 protein kinase binding
GO:0019903 protein phosphatase binding
GO:0019904 protein domain specific binding
GO:0031698 beta-2 adrenergic receptor binding
GO:0031952 regulation of protein autophosphorylation
GO:0032516 positive regulation of phosphoprotein phosphatase activity
GO:0035307 positive regulation of protein dephosphorylation
GO:0035970 peptidyl-threonine dephosphorylation
GO:0042176 regulation of protein catabolic process
GO:0042308 negative regulation of protein import into nucleus
GO:0042802 identical protein binding
GO:0043005 neuron projection
GO:0043065 positive regulation of apoptotic process
GO:0043195 terminal bouton
GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043422 protein kinase B binding
GO:0044325 transmembrane transporter binding
GO:0044877 protein-containing complex binding
GO:0045121 membrane raft
GO:0045202 synapse
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity
GO:0048156 tau protein binding
GO:0050811 GABA receptor binding
GO:0051321 meiotic cell cycle
GO:0051721 protein phosphatase 2A binding
GO:0051726 regulation of cell cycle
GO:0071333 cellular response to glucose stimulus
GO:0071902 positive regulation of protein serine/threonine kinase activity
GO:0106306 protein serine phosphatase activity
GO:0106307 protein threonine phosphatase activity
GO:1901020 negative regulation of calcium ion transmembrane transporter activity
GO:1904528 positive regulation of microtubule binding
GO:1990405 protein antigen binding

Subcellular Location

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Subcellular Location
Chromosome
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR004843 Calcineurin-like phosphoesterase domain, ApaH typeDomainDomain
IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphataseDomainDomain
IPR029052 Metallo-dependent phosphatase-likeFamilyHomologous superfamily

Diseases

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