Entity Details

Primary name KPCB_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP68404
EntryNameKPCB_MOUSE
FullNameProtein kinase C beta type
TaxID10090
Evidenceevidence at protein level
Length671
SequenceStatuscomplete
DateCreated1987-08-13
DateModified2021-06-02

Ontological Relatives

GenesPrkcb

GO terms

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GOName
GO:0001666 response to hypoxia
GO:0002250 adaptive immune response
GO:0003682 chromatin binding
GO:0004674 protein serine/threonine kinase activity
GO:0004697 protein kinase C activity
GO:0004698 calcium-dependent protein kinase C activity
GO:0005080 protein kinase C binding
GO:0005246 calcium channel regulator activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006468 protein phosphorylation
GO:0006816 calcium ion transport
GO:0006874 cellular calcium ion homeostasis
GO:0006915 apoptotic process
GO:0008091 spectrin
GO:0008270 zinc ion binding
GO:0010827 regulation of glucose transmembrane transport
GO:0010829 negative regulation of glucose transmembrane transport
GO:0014059 regulation of dopamine secretion
GO:0016020 membrane
GO:0018105 peptidyl-serine phosphorylation
GO:0030374 nuclear receptor coactivator activity
GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway
GO:0031526 brush border membrane
GO:0035403 histone kinase activity (H3-T6 specific)
GO:0035408 histone H3-T6 phosphorylation
GO:0035556 intracellular signal transduction
GO:0040008 regulation of growth
GO:0042113 B cell activation
GO:0042393 histone binding
GO:0042493 response to drug
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0044305 calyx of Held
GO:0045766 positive regulation of angiogenesis
GO:0046627 negative regulation of insulin receptor signaling pathway
GO:0050681 androgen receptor binding
GO:0050853 B cell receptor signaling pathway
GO:0050861 positive regulation of B cell receptor signaling pathway
GO:0051092 positive regulation of NF-kappaB transcription factor activity
GO:0071322 cellular response to carbohydrate stimulus
GO:0099171 presynaptic modulation of chemical synaptic transmission
GO:0099523 presynaptic cytosol
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:2000300 regulation of synaptic vesicle exocytosis

Subcellular Location

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Subcellular Location
Cytoplasm
Membrane
Nucleus

Domains

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DomainNameCategoryType
IPR000008 C2 domainDomainDomain
IPR000719 Protein kinase domainDomainDomain
IPR000961 AGC-kinase, C-terminalDomainDomain
IPR002219 Protein kinase C-like, phorbol ester/diacylglycerol-binding domainDomainDomain
IPR008271 Serine/threonine-protein kinase, active siteSiteActive site
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR014375 Protein kinase C, alpha/beta/gamma typesFamilyFamily
IPR017441 Protein kinase, ATP binding siteSiteBinding site
IPR017892 Protein kinase, C-terminalDomainDomain
IPR020454 Diacylglycerol/phorbol-ester bindingDomainDomain
IPR034664 Classical protein kinase C beta, catalytic domainDomainDomain
IPR035892 C2 domain superfamilyFamilyHomologous superfamily

Diseases

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