Entity Details

Primary name TRAF5_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP70191
EntryNameTRAF5_MOUSE
FullNameTNF receptor-associated factor 5
TaxID10090
Evidenceevidence at protein level
Length558
SequenceStatuscomplete
DateCreated2003-05-09
DateModified2021-06-02

Ontological Relatives

GenesTraf5

GO terms

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GOName
GO:0004842 ubiquitin-protein transferase activity
GO:0005164 tumor necrosis factor receptor binding
GO:0005813 centrosome
GO:0005829 cytosol
GO:0006915 apoptotic process
GO:0007165 signal transduction
GO:0008270 zinc ion binding
GO:0008284 positive regulation of cell population proliferation
GO:0009898 cytoplasmic side of plasma membrane
GO:0023019 signal transduction involved in regulation of gene expression
GO:0031625 ubiquitin protein ligase binding
GO:0031996 thioesterase binding
GO:0033209 tumor necrosis factor-mediated signaling pathway
GO:0035631 CD40 receptor complex
GO:0042802 identical protein binding
GO:0042981 regulation of apoptotic process
GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0046330 positive regulation of JNK cascade
GO:0048255 mRNA stabilization
GO:0051091 positive regulation of DNA-binding transcription factor activity
GO:0051092 positive regulation of NF-kappaB transcription factor activity
GO:0070534 protein K63-linked ubiquitination
GO:0097400 interleukin-17-mediated signaling pathway

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR001293 Zinc finger, TRAF-typeDomainDomain
IPR001841 Zinc finger, RING-typeDomainDomain
IPR002083 MATH/TRAF domainDomainDomain
IPR008974 TRAF-likeFamilyHomologous superfamily
IPR012227 TNF receptor-associated factor TRAF, metazoaFamilyFamily
IPR013083 Zinc finger, RING/FYVE/PHD-typeFamilyHomologous superfamily
IPR017907 Zinc finger, RING-type, conserved siteSiteConserved site
IPR018957 Zinc finger, C3HC4 RING-typeDomainDomain
IPR027130 TNF receptor-associated factor 5FamilyFamily
IPR037308 TNF receptor-associated factor 5, MATH domainDomainDomain
IPR043211 TNF receptor-associated factor TRAFFamilyFamily

Diseases

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