Entity Details

Primary name PACR_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP70205
EntryNamePACR_MOUSE
FullNamePituitary adenylate cyclase-activating polypeptide type I receptor
TaxID10090
Evidenceevidence at protein level
Length496
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesAdcyap1r1

GO terms

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GOName
GO:0004930 G protein-coupled receptor activity
GO:0004999 vasoactive intestinal polypeptide receptor activity
GO:0005737 cytoplasm
GO:0005768 endosome
GO:0005791 rough endoplasmic reticulum
GO:0005886 plasma membrane
GO:0005901 caveola
GO:0005923 bicellular tight junction
GO:0007166 cell surface receptor signaling pathway
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway
GO:0007202 activation of phospholipase C activity
GO:0007275 multicellular organism development
GO:0007283 spermatogenesis
GO:0008179 adenylate cyclase binding
GO:0008528 G protein-coupled peptide receptor activity
GO:0009986 cell surface
GO:0010524 positive regulation of calcium ion transport into cytosol
GO:0016021 integral component of membrane
GO:0017046 peptide hormone binding
GO:0019933 cAMP-mediated signaling
GO:0030154 cell differentiation
GO:0031267 small GTPase binding
GO:0042923 neuropeptide binding
GO:0043005 neuron projection
GO:0043231 intracellular membrane-bounded organelle
GO:0043235 receptor complex
GO:0043950 positive regulation of cAMP-mediated signaling
GO:0051057 positive regulation of small GTPase mediated signal transduction
GO:0060548 negative regulation of cell death
GO:0060732 positive regulation of inositol phosphate biosynthetic process

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000832 GPCR, family 2, secretin-likeFamilyFamily
IPR001879 GPCR, family 2, extracellular hormone receptor domainDomainDomain
IPR002285 GPCR, family 2, pituitary adenylate cyclase activating polypeptide type 1 receptorFamilyFamily
IPR017981 GPCR, family 2-likeDomainDomain
IPR017983 GPCR, family 2, secretin-like, conserved siteSiteConserved site
IPR036445 GPCR family 2, extracellular hormone receptor domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
PACR_MOUSEIGF1R_MOUSEMINT17332755 details