Entity Details

Primary name F262_MOUSE
Entity type UniProt
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Details

AccessionP70265
EntryNameF262_MOUSE
FullName6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2
TaxID10090
Evidenceevidence at protein level
Length519
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesPfkfb2

GO terms

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GOName
GO:0003873 6-phosphofructo-2-kinase activity
GO:0004331 fructose-2,6-bisphosphate 2-phosphatase activity
GO:0005524 ATP binding
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006000 fructose metabolic process
GO:0006003 fructose 2,6-bisphosphate metabolic process
GO:0006007 glucose catabolic process
GO:0006089 lactate metabolic process
GO:0006090 pyruvate metabolic process
GO:0006096 glycolytic process
GO:0009749 response to glucose
GO:0019900 kinase binding
GO:0019901 protein kinase binding
GO:0032024 positive regulation of insulin secretion
GO:0033133 positive regulation of glucokinase activity

Subcellular Location

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Domains

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DomainNameCategoryType
IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active siteSiteActive site
IPR003094 Fructose-2,6-bisphosphataseFamilyFamily
IPR013078 Histidine phosphatase superfamily, clade-1FamilyFamily
IPR013079 6-phosphofructo-2-kinaseDomainDomain
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR029033 Histidine phosphatase superfamilyFamilyHomologous superfamily

Diseases

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Interactions

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