Entity Details

Primary name F261_MOUSE
Entity type UniProt
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Details

AccessionP70266
EntryNameF261_MOUSE
FullName6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1
TaxID10090
Evidenceevidence at protein level
Length471
SequenceStatuscomplete
DateCreated1998-07-15
DateModified2021-06-02

Ontological Relatives

GenesPfkfb1

GO terms

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GOName
GO:0003873 6-phosphofructo-2-kinase activity
GO:0004331 fructose-2,6-bisphosphate 2-phosphatase activity
GO:0005524 ATP binding
GO:0005829 cytosol
GO:0006000 fructose metabolic process
GO:0006003 fructose 2,6-bisphosphate metabolic process
GO:0019900 kinase binding
GO:0031100 animal organ regeneration
GO:0032868 response to insulin
GO:0033133 positive regulation of glucokinase activity
GO:0033762 response to glucagon
GO:0042594 response to starvation
GO:0042802 identical protein binding
GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex
GO:0046835 carbohydrate phosphorylation
GO:0051384 response to glucocorticoid
GO:0051591 response to cAMP
GO:0070095 fructose-6-phosphate binding

Subcellular Location

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Domains

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DomainNameCategoryType
IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active siteSiteActive site
IPR003094 Fructose-2,6-bisphosphataseFamilyFamily
IPR013078 Histidine phosphatase superfamily, clade-1FamilyFamily
IPR013079 6-phosphofructo-2-kinaseDomainDomain
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR029033 Histidine phosphatase superfamilyFamilyHomologous superfamily

Diseases

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Interactions

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