Entity Details

Primary name PITX1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP70314
EntryNamePITX1_MOUSE
FullNamePituitary homeobox 1
TaxID10090
Evidenceevidence at transcript level
Length315
SequenceStatuscomplete
DateCreated1998-07-15
DateModified2021-06-02

Ontological Relatives

GenesPitx1

GO terms

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GOName
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001501 skeletal system development
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005667 transcription regulator complex
GO:0005737 cytoplasm
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription by RNA polymerase II
GO:0009653 anatomical structure morphogenesis
GO:0014707 branchiomeric skeletal muscle development
GO:0021983 pituitary gland development
GO:0035116 embryonic hindlimb morphogenesis
GO:0035137 hindlimb morphogenesis
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048625 myoblast fate commitment
GO:0051216 cartilage development
GO:1990837 sequence-specific double-stranded DNA binding

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR001356 Homeobox domainDomainDomain
IPR003654 OAR domainDomainDomain
IPR009057 Homeobox-like domain superfamilyFamilyHomologous superfamily
IPR016233 Homeobox protein Pitx/unc30FamilyFamily
IPR017970 Homeobox, conserved siteSiteConserved site

Diseases

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Interactions

3 interactions