Entity Details

Primary name TBX1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP70323
EntryNameTBX1_MOUSE
FullNameT-box transcription factor TBX1
TaxID10090
Evidenceevidence at protein level
Length479
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesTbx1

GO terms

Show/Hide Table
GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001525 angiogenesis
GO:0001568 blood vessel development
GO:0001569 branching involved in blood vessel morphogenesis
GO:0001708 cell fate specification
GO:0001755 neural crest cell migration
GO:0001934 positive regulation of protein phosphorylation
GO:0001945 lymph vessel development
GO:0001974 blood vessel remodeling
GO:0002053 positive regulation of mesenchymal cell proliferation
GO:0003007 heart morphogenesis
GO:0003148 outflow tract septum morphogenesis
GO:0003151 outflow tract morphogenesis
GO:0003677 DNA binding
GO:0005634 nucleus
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007368 determination of left/right symmetry
GO:0007389 pattern specification process
GO:0007498 mesoderm development
GO:0007507 heart development
GO:0007517 muscle organ development
GO:0007605 sensory perception of sound
GO:0008283 cell population proliferation
GO:0008284 positive regulation of cell population proliferation
GO:0009952 anterior/posterior pattern specification
GO:0021644 vagus nerve morphogenesis
GO:0030855 epithelial cell differentiation
GO:0030878 thyroid gland development
GO:0035176 social behavior
GO:0035909 aorta morphogenesis
GO:0042471 ear morphogenesis
GO:0042472 inner ear morphogenesis
GO:0042473 outer ear morphogenesis
GO:0042474 middle ear morphogenesis
GO:0042475 odontogenesis of dentin-containing tooth
GO:0042693 muscle cell fate commitment
GO:0042803 protein homodimerization activity
GO:0043410 positive regulation of MAPK cascade
GO:0043565 sequence-specific DNA binding
GO:0043587 tongue morphogenesis
GO:0044344 cellular response to fibroblast growth factor stimulus
GO:0045596 negative regulation of cell differentiation
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048384 retinoic acid receptor signaling pathway
GO:0048514 blood vessel morphogenesis
GO:0048538 thymus development
GO:0048644 muscle organ morphogenesis
GO:0048701 embryonic cranial skeleton morphogenesis
GO:0048703 embryonic viscerocranium morphogenesis
GO:0048752 semicircular canal morphogenesis
GO:0048844 artery morphogenesis
GO:0050679 positive regulation of epithelial cell proliferation
GO:0060017 parathyroid gland development
GO:0060022 hard palate development
GO:0060023 soft palate development
GO:0060037 pharyngeal system development
GO:0060325 face morphogenesis
GO:0060415 muscle tissue morphogenesis
GO:0060982 coronary artery morphogenesis
GO:0070166 enamel mineralization
GO:0071300 cellular response to retinoic acid
GO:0071600 otic vesicle morphogenesis
GO:0072513 positive regulation of secondary heart field cardioblast proliferation
GO:0090103 cochlea morphogenesis
GO:0097152 mesenchymal cell apoptotic process
GO:1990837 sequence-specific double-stranded DNA binding
GO:2000027 regulation of animal organ morphogenesis
GO:2001037 positive regulation of tongue muscle cell differentiation
GO:2001054 negative regulation of mesenchymal cell apoptotic process

Subcellular Location

Show/Hide Table
Subcellular Location
Nucleus

Domains

Show/Hide Table
DomainNameCategoryType
IPR001699 Transcription factor, T-boxFamilyFamily
IPR008967 p53-like transcription factor, DNA-bindingFamilyHomologous superfamily
IPR018186 Transcription factor, T-box, conserved siteSiteConserved site
IPR036960 T-box superfamilyFamilyHomologous superfamily

Diseases

Show/Hide Table

Interactions

4 interactions