Entity Details

Primary name TBX6_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP70327
EntryNameTBX6_MOUSE
FullNameT-box transcription factor TBX6
TaxID10090
Evidenceevidence at transcript level
Length436
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesTbx6

GO terms

Show/Hide Table
GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0001707 mesoderm formation
GO:0001708 cell fate specification
GO:0001947 heart looping
GO:0003205 cardiac chamber development
GO:0005634 nucleus
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007417 central nervous system development
GO:0008284 positive regulation of cell population proliferation
GO:0010977 negative regulation of neuron projection development
GO:0014043 negative regulation of neuron maturation
GO:0023019 signal transduction involved in regulation of gene expression
GO:0032525 somite rostral/caudal axis specification
GO:0043433 negative regulation of DNA-binding transcription factor activity
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:1990837 sequence-specific double-stranded DNA binding

Subcellular Location

Show/Hide Table
Subcellular Location
Nucleus

Domains

Show/Hide Table
DomainNameCategoryType
IPR001699 Transcription factor, T-boxFamilyFamily
IPR002070 Transcription factor, BrachyuryFamilyFamily
IPR008967 p53-like transcription factor, DNA-bindingFamilyHomologous superfamily
IPR018186 Transcription factor, T-box, conserved siteSiteConserved site
IPR036960 T-box superfamilyFamilyHomologous superfamily

Diseases

Show/Hide Table

Interactions

3 interactions