Entity Details

Primary name B2CL2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP70345
EntryNameB2CL2_MOUSE
FullNameBcl-2-like protein 2
TaxID10090
Evidenceevidence at protein level
Length193
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesBcl2l2

GO terms

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GOName
GO:0002931 response to ischemia
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005741 mitochondrial outer membrane
GO:0005829 cytosol
GO:0006915 apoptotic process
GO:0007420 brain development
GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage
GO:0031966 mitochondrial membrane
GO:0035795 negative regulation of mitochondrial membrane permeability
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0043066 negative regulation of apoptotic process
GO:0044877 protein-containing complex binding
GO:0046982 protein heterodimerization activity
GO:0051400 BH domain binding
GO:0060011 Sertoli cell proliferation
GO:0071392 cellular response to estradiol stimulus
GO:0090201 negative regulation of release of cytochrome c from mitochondria
GO:0097136 Bcl-2 family protein complex
GO:0097192 extrinsic apoptotic signaling pathway in absence of ligand
GO:0097718 disordered domain specific binding
GO:1904646 cellular response to amyloid-beta
GO:1905430 cellular response to glycine
GO:2001243 negative regulation of intrinsic apoptotic signaling pathway

Subcellular Location

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Subcellular Location
Mitochondrion membrane

Domains

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DomainNameCategoryType
IPR002475 Bcl2-likeFamilyFamily
IPR003093 Apoptosis regulator, Bcl-2 protein, BH4DomainDomain
IPR013280 Apoptosis regulator, Bcl-WFamilyFamily
IPR020717 Apoptosis regulator, Bcl-2, BH1 motif, conserved siteSiteConserved site
IPR020726 Apoptosis regulator, Bcl-2, BH2 motif, conserved siteSiteConserved site
IPR020731 Apoptosis regulator, Bcl-2, BH4 motif, conserved siteSiteConserved site
IPR026298 Bcl-2 familyFamilyFamily
IPR036834 Bcl-2-like superfamilyFamilyHomologous superfamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
B2CL2_MOUSEPAXI_MOUSEBioGRID14699151 details
B2CL2_MOUSEHIF3A_MOUSEBioGRID21546903 details