Entity Details

Primary name TERF1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP70371
EntryNameTERF1_MOUSE
FullNameTelomeric repeat-binding factor 1
TaxID10090
Evidenceevidence at protein level
Length421
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesTerf1

GO terms

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GOName
GO:0000723 telomere maintenance
GO:0000781 chromosome, telomeric region
GO:0000783 nuclear telomere cap complex
GO:0001650 fibrillar center
GO:0003691 double-stranded telomeric DNA binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005819 spindle
GO:0007004 telomere maintenance via telomerase
GO:0008017 microtubule binding
GO:0008022 protein C-terminus binding
GO:0008156 negative regulation of DNA replication
GO:0008301 DNA binding, bending
GO:0016604 nuclear body
GO:0032211 negative regulation of telomere maintenance via telomerase
GO:0042162 telomeric DNA binding
GO:0042493 response to drug
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0045141 meiotic telomere clustering
GO:0051301 cell division
GO:0051974 negative regulation of telomerase activity
GO:0061820 telomeric D-loop disassembly
GO:0070187 shelterin complex
GO:0071532 ankyrin repeat binding
GO:0098505 G-rich strand telomeric DNA binding
GO:1904792 positive regulation of shelterin complex assembly
GO:1904850 negative regulation of establishment of protein localization to telomere
GO:1904911 negative regulation of establishment of RNA localization to telomere
GO:1905778 negative regulation of exonuclease activity
GO:1905839 negative regulation of telomeric D-loop disassembly

Subcellular Location

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Subcellular Location
Chromosome
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR001005 SANT/Myb domainDomainDomain
IPR009057 Homeobox-like domain superfamilyFamilyHomologous superfamily
IPR013867 Telomere repeat-binding factor, dimerisation domainDomainDomain
IPR017357 Telomeric repeat-binding factor 1/2FamilyFamily
IPR017930 Myb domainDomainDomain
IPR036507 Telomere repeat-binding factor, dimerisation domain superfamilyFamilyHomologous superfamily

Diseases

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