Entity Details

Primary name TP53B_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP70399
EntryNameTP53B_MOUSE
FullNameTP53-binding protein 1
TaxID10090
Evidenceevidence at protein level
Length1969
SequenceStatuscomplete
DateCreated1998-07-15
DateModified2021-06-02

Ontological Relatives

GenesTrp53bp1

GO terms

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GOName
GO:0000077 DNA damage checkpoint signaling
GO:0000776 kinetochore
GO:0000781 chromosome, telomeric region
GO:0002039 p53 binding
GO:0003684 damaged DNA binding
GO:0003712 transcription coregulator activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005657 replication fork
GO:0005737 cytoplasm
GO:0006281 DNA repair
GO:0006303 double-strand break repair via nonhomologous end joining
GO:0006355 regulation of transcription, DNA-templated
GO:0006974 cellular response to DNA damage stimulus
GO:0008134 transcription factor binding
GO:0016604 nuclear body
GO:0035064 methylated histone binding
GO:0035861 site of double-strand break
GO:0042162 telomeric DNA binding
GO:0042393 histone binding
GO:0043565 sequence-specific DNA binding
GO:0045830 positive regulation of isotype switching
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0051260 protein homooligomerization
GO:0061649 ubiquitin modification-dependent histone binding
GO:0071481 cellular response to X-ray
GO:1990391 DNA repair complex
GO:2000042 negative regulation of double-strand break repair via homologous recombination

Subcellular Location

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Subcellular Location
Chromosome
Nucleus

Domains

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DomainNameCategoryType
IPR001357 BRCT domainDomainDomain
IPR002999 Tudor domainDomainDomain
IPR014722 Ribosomal protein L2, domain 2FamilyHomologous superfamily
IPR015125 Tumour suppressor p53-binding protein-1 Tudor domainDomainDomain
IPR036420 BRCT domain superfamilyFamilyHomologous superfamily

Diseases

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