Entity Details

Primary name CXCR4_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP70658
EntryNameCXCR4_MOUSE
FullNameC-X-C chemokine receptor type 4
TaxID10090
Evidenceevidence at protein level
Length359
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesCxcr4

GO terms

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GOName
GO:0001569 branching involved in blood vessel morphogenesis
GO:0001667 ameboidal-type cell migration
GO:0001764 neuron migration
GO:0001822 kidney development
GO:0001934 positive regulation of protein phosphorylation
GO:0002064 epithelial cell development
GO:0003281 ventricular septum development
GO:0003779 actin binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005764 lysosome
GO:0005768 endosome
GO:0005769 early endosome
GO:0005770 late endosome
GO:0005886 plasma membrane
GO:0005911 cell-cell junction
GO:0006955 immune response
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0007281 germ cell development
GO:0007399 nervous system development
GO:0007420 brain development
GO:0008045 motor neuron axon guidance
GO:0008354 germ cell migration
GO:0009887 animal organ morphogenesis
GO:0009897 external side of plasma membrane
GO:0009986 cell surface
GO:0016021 integral component of membrane
GO:0016477 cell migration
GO:0016493 C-C chemokine receptor activity
GO:0019722 calcium-mediated signaling
GO:0019957 C-C chemokine binding
GO:0022008 neurogenesis
GO:0022029 telencephalon cell migration
GO:0030155 regulation of cell adhesion
GO:0030334 regulation of cell migration
GO:0030335 positive regulation of cell migration
GO:0030426 growth cone
GO:0031252 cell leading edge
GO:0031410 cytoplasmic vesicle
GO:0031625 ubiquitin protein ligase binding
GO:0032027 myosin light chain binding
GO:0032991 protein-containing complex
GO:0035470 positive regulation of vascular wound healing
GO:0035701 hematopoietic stem cell migration
GO:0035904 aorta development
GO:0038147 C-X-C motif chemokine 12 receptor activity
GO:0038160 CXCL12-activated CXCR4 signaling pathway
GO:0042098 T cell proliferation
GO:0042802 identical protein binding
GO:0043067 regulation of programmed cell death
GO:0043130 ubiquitin binding
GO:0043217 myelin maintenance
GO:0045446 endothelial cell differentiation
GO:0048699 generation of neurons
GO:0048714 positive regulation of oligodendrocyte differentiation
GO:0050769 positive regulation of neurogenesis
GO:0050792 regulation of viral process
GO:0050920 regulation of chemotaxis
GO:0050921 positive regulation of chemotaxis
GO:0050965 detection of temperature stimulus involved in sensory perception of pain
GO:0050966 detection of mechanical stimulus involved in sensory perception of pain
GO:0051924 regulation of calcium ion transport
GO:0060048 cardiac muscle contraction
GO:0060326 cell chemotaxis
GO:0061154 endothelial tube morphogenesis
GO:0061351 neural precursor cell proliferation
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0071345 cellular response to cytokine stimulus
GO:0090280 positive regulation of calcium ion import
GO:0120162 positive regulation of cold-induced thermogenesis
GO:1903861 positive regulation of dendrite extension
GO:1905322 positive regulation of mesenchymal stem cell migration
GO:2000448 positive regulation of macrophage migration inhibitory factor signaling pathway

Subcellular Location

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Subcellular Location
Cell junction
Cell membrane
Early endosome
Late endosome
Lysosome

Domains

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DomainNameCategoryType
IPR000276 G protein-coupled receptor, rhodopsin-likeFamilyFamily
IPR000355 Chemokine receptor familyFamilyFamily
IPR001277 CXC chemokine receptor 4/atypical chemokine receptor 2FamilyFamily
IPR017452 GPCR, rhodopsin-like, 7TMDomainDomain
IPR022726 CXC chemokine receptor 4 N-terminal domainDomainDomain

Diseases

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