Entity Details

Primary name LDB1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP70662
EntryNameLDB1_MOUSE
FullNameLIM domain-binding protein 1
TaxID10090
Evidenceevidence at protein level
Length411
SequenceStatuscomplete
DateCreated1998-07-15
DateModified2021-06-02

Ontological Relatives

GenesLdb1

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery
GO:0001702 gastrulation with mouth forming second
GO:0001942 hair follicle development
GO:0003682 chromatin binding
GO:0003712 transcription coregulator activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005667 transcription regulator complex
GO:0006366 transcription by RNA polymerase II
GO:0007399 nervous system development
GO:0009948 anterior/posterior axis specification
GO:0010669 epithelial structure maintenance
GO:0016055 Wnt signaling pathway
GO:0019899 enzyme binding
GO:0021549 cerebellum development
GO:0021702 cerebellar Purkinje cell differentiation
GO:0022607 cellular component assembly
GO:0030154 cell differentiation
GO:0030182 neuron differentiation
GO:0030274 LIM domain binding
GO:0030334 regulation of cell migration
GO:0031252 cell leading edge
GO:0032991 protein-containing complex
GO:0034243 regulation of transcription elongation from RNA polymerase II promoter
GO:0035019 somatic stem cell population maintenance
GO:0042803 protein homodimerization activity
GO:0043549 regulation of kinase activity
GO:0043621 protein self-association
GO:0043973 histone H3-K4 acetylation
GO:0045647 negative regulation of erythrocyte differentiation
GO:0045785 positive regulation of cell adhesion
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046985 positive regulation of hemoglobin biosynthetic process
GO:0048382 mesendoderm development
GO:0051893 regulation of focal adhesion assembly
GO:0060319 primitive erythrocyte differentiation
GO:0060322 head development
GO:0090575 RNA polymerase II transcription regulator complex
GO:0140297 DNA-binding transcription factor binding
GO:1990907 beta-catenin-TCF complex

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR029005 LIM-domain binding protein/SEUSSFamilyFamily
IPR030167 LIM domain-binding protein 1FamilyFamily
IPR041363 LIM interaction domainDomainDomain

Diseases

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Interactions

28 interactions

InteractorPartnerSourcesPublicationsLink
LDB1_MOUSELHX3_MOUSEMINT18583962 details
LDB1_MOUSEISL1_MOUSEIntAct, MINT18583962 20211142 details
LDB1_MOUSEISL2_MOUSEBioGRID, IntAct20211142 details
LDB1_MOUSECSDC2_MOUSEBioGRID, IntAct20211142 details
LDB1_MOUSELMO3_MOUSEBioGRID, IntAct20211142 details
LDB1_MOUSERBTN1_MOUSEBioGRID, IntAct20211142 details
LDB1_MOUSELMX1A_MOUSEBioGRID, IntAct20211142 details
LDB1_MOUSELHX2_MOUSEBioGRID, IntAct20211142 details
LDB1_MOUSELHX1_MOUSEBioGRID, IntAct20211142 details
LDB1_MOUSEHXD1_MOUSEBioGRID, IntAct20211142 details
LDB1_MOUSEALX4_MOUSEBioGRID, IntAct20211142 details
LDB1_MOUSELHX4_MOUSEBioGRID, IntAct20211142 details
LDB1_MOUSELHX5_MOUSEBioGRID, IntAct20211142 details
LDB1_MOUSELHX9_MOUSEBioGRID, IntAct20211142 details
LDB1_MOUSELMX1B_MOUSEBioGRID, IntAct20211142 details
LDB1_MOUSELMO4_MOUSEBioGRID, IntAct20211142 details
LDB1_MOUSERBTN2_MOUSEBioGRID, IntAct20211142 26764384 details
LDB1_MOUSETADBP_MOUSEBioGRID, IntAct20211142 details
LDB1_MOUSESSBP2_MOUSEBioGRID, IntAct20211142 details
LDB1_MOUSEZN593_MOUSEBioGRID, IntAct20211142 details
LDB1_MOUSEPYGO1_MOUSEBioGRID, IntAct20211142 details
LDB1_MOUSESSBP3_MOUSEBioGRID, IntAct20211142 31186351 details
LDB1_MOUSETAL1_MOUSEBioGRID, MINT, UniProt15920471 16407974 19799863 details
LDB1_MOUSEITF2_MOUSEMINT16407974 details
LDB1_MOUSEMTG16_MOUSEMINT16407974 details
LDB1_MOUSEPITX2_MOUSEBioGRID12464179 details
LDB1_MOUSEGATA1_MOUSEBioGRID15920471 details
LDB1_MOUSE1433Z_MOUSEBioGRID16959763 details