Entity Details

Primary name DHB5_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP70694
EntryNameDHB5_MOUSE
FullNameEstradiol 17 beta-dehydrogenase 5
TaxID10090
Evidenceevidence at protein level
Length323
SequenceStatuscomplete
DateCreated1999-07-15
DateModified2021-06-02

Ontological Relatives

GenesAkr1c6

GO terms

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GOName
GO:0001758 retinal dehydrogenase activity
GO:0004032 alditol:NADP+ 1-oxidoreductase activity
GO:0004033 aldo-keto reductase (NADP) activity
GO:0004303 estradiol 17-beta-dehydrogenase activity
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006693 prostaglandin metabolic process
GO:0006694 steroid biosynthetic process
GO:0008202 steroid metabolic process
GO:0016229 steroid dehydrogenase activity
GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
GO:0032052 bile acid binding
GO:0042448 progesterone metabolic process
GO:0042493 response to drug
GO:0043627 response to estrogen
GO:0044597 daunorubicin metabolic process
GO:0044598 doxorubicin metabolic process
GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity
GO:0047023 androsterone dehydrogenase activity
GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity
GO:0047086 ketosteroid monooxygenase activity
GO:0047743 chlordecone reductase activity
GO:0047834 D-threo-aldose 1-dehydrogenase activity
GO:0048025 negative regulation of mRNA splicing, via spliceosome
GO:0071395 cellular response to jasmonic acid stimulus

Subcellular Location

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Domains

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DomainNameCategoryType
IPR018170 Aldo/keto reductase, conserved siteSiteConserved site
IPR020471 Aldo-keto reductaseFamilyFamily
IPR023210 NADP-dependent oxidoreductase domainDomainDomain
IPR036812 NADP-dependent oxidoreductase domain superfamilyFamilyHomologous superfamily
IPR044482 Aldo-keto reductase family 1 member CFamilyFamily

Diseases

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Interactions

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