Entity Details

Primary name C2TA_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP79621
EntryNameC2TA_MOUSE
FullNameMHC class II transactivator
TaxID10090
Evidenceevidence at protein level
Length1155
SequenceStatuscomplete
DateCreated1998-12-15
DateModified2021-06-02

Ontological Relatives

GenesCiita

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000976 transcription cis-regulatory region binding
GO:0005524 ATP binding
GO:0005525 GTP binding
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0006954 inflammatory response
GO:0007568 aging
GO:0008022 protein C-terminus binding
GO:0009986 cell surface
GO:0016605 PML body
GO:0016746 acyltransferase activity
GO:0034341 response to interferon-gamma
GO:0044877 protein-containing complex binding
GO:0045345 positive regulation of MHC class I biosynthetic process
GO:0045348 positive regulation of MHC class II biosynthetic process
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046597 negative regulation of viral entry into host cell
GO:0046677 response to antibiotic
GO:0071257 cellular response to electrical stimulus
GO:0071346 cellular response to interferon-gamma
GO:0071360 cellular response to exogenous dsRNA
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR001611 Leucine-rich repeatRepeatRepeat
IPR007111 NACHT nucleoside triphosphataseDomainDomain
IPR008095 MHC class II transactivatorFamilyFamily
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR032675 Leucine-rich repeat domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

8 interactions