Entity Details

Primary name IRX1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP81068
EntryNameIRX1_MOUSE
FullNameIroquois-class homeodomain protein IRX-1
TaxID10090
Evidenceevidence at protein level
Length480
SequenceStatuscomplete
DateCreated1998-07-15
DateModified2021-06-02

Ontological Relatives

GenesIrx1

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0001656 metanephros development
GO:0005634 nucleus
GO:0006357 regulation of transcription by RNA polymerase II
GO:0030182 neuron differentiation
GO:0043565 sequence-specific DNA binding
GO:0048468 cell development
GO:0072086 specification of loop of Henle identity
GO:0072272 proximal/distal pattern formation involved in metanephric nephron development
GO:1990837 sequence-specific double-stranded DNA binding

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR001356 Homeobox domainDomainDomain
IPR003893 Iroquois-class homeodomain proteinDomainDomain
IPR008422 Homeobox KN domainDomainDomain
IPR009057 Homeobox-like domain superfamilyFamilyHomologous superfamily
IPR017970 Homeobox, conserved siteSiteConserved site

Diseases

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Interactions

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InteractorPartnerSourcesPublicationsLink