Entity Details

Primary name NUCB2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP81117
EntryNameNUCB2_MOUSE
FullNameNucleobindin-2
TaxID10090
Evidenceevidence at protein level
Length420
SequenceStatuscomplete
DateCreated1998-07-15
DateModified2021-06-02

Ontological Relatives

GenesNucb2

GO terms

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GOName
GO:0001965 G-protein alpha-subunit binding
GO:0003677 DNA binding
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005164 tumor necrosis factor receptor binding
GO:0005509 calcium ion binding
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005640 nuclear outer membrane
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005793 endoplasmic reticulum-Golgi intermediate compartment
GO:0005797 Golgi medial cisterna
GO:0006874 cellular calcium ion homeostasis
GO:0007264 small GTPase mediated signal transduction
GO:0032099 negative regulation of appetite
GO:0043204 perikaryon
GO:0043951 negative regulation of cAMP-mediated signaling
GO:0045599 negative regulation of fat cell differentiation
GO:0046321 positive regulation of fatty acid oxidation
GO:0046627 negative regulation of insulin receptor signaling pathway
GO:0070093 negative regulation of glucagon secretion
GO:1901142 insulin metabolic process
GO:2000845 positive regulation of testosterone secretion

Subcellular Location

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Subcellular Location
Cytoplasm
Endoplasmic reticulum
Golgi apparatus
Membrane
Nucleus envelope
Perikaryon
Secreted

Domains

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DomainNameCategoryType
IPR002048 EF-hand domainDomainDomain
IPR011992 EF-hand domain pairFamilyHomologous superfamily
IPR018247 EF-Hand 1, calcium-binding siteSiteBinding site
IPR028813 Nucleobindin-2FamilyFamily
IPR040250 NucleobindinFamilyFamily

Diseases

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Interactions

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InteractorPartnerSourcesPublicationsLink