Entity Details

Primary name AP2M1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP84091
EntryNameAP2M1_MOUSE
FullNameAP-2 complex subunit mu
TaxID10090
Evidenceevidence at protein level
Length435
SequenceStatuscomplete
DateCreated2004-08-16
DateModified2021-06-02

Ontological Relatives

GenesAp2m1

GO terms

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GOName
GO:0002092 positive regulation of receptor internalization
GO:0005048 signal sequence binding
GO:0005739 mitochondrion
GO:0005886 plasma membrane
GO:0005905 clathrin-coated pit
GO:0006886 intracellular protein transport
GO:0006897 endocytosis
GO:0006900 vesicle budding from membrane
GO:0008289 lipid binding
GO:0016192 vesicle-mediated transport
GO:0030122 AP-2 adaptor complex
GO:0030141 secretory granule
GO:0031410 cytoplasmic vesicle
GO:0031623 receptor internalization
GO:0035615 clathrin adaptor activity
GO:0043231 intracellular membrane-bounded organelle
GO:0044325 transmembrane transporter binding
GO:0048488 synaptic vesicle endocytosis
GO:0050750 low-density lipoprotein particle receptor binding
GO:0065003 protein-containing complex assembly
GO:0072583 clathrin-dependent endocytosis
GO:0097494 regulation of vesicle size
GO:0097718 disordered domain specific binding
GO:0098793 presynapse
GO:0098794 postsynapse
GO:0098884 postsynaptic neurotransmitter receptor internalization
GO:0098978 glutamatergic synapse
GO:1900244 positive regulation of synaptic vesicle endocytosis
GO:1903077 negative regulation of protein localization to plasma membrane

Subcellular Location

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Subcellular Location
Cell membrane
Membrane

Domains

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DomainNameCategoryType
IPR001392 Clathrin adaptor, mu subunitFamilyFamily
IPR011012 Longin-like domain superfamilyFamilyHomologous superfamily
IPR018240 Clathrin adaptor, mu subunit, conserved siteSiteConserved site
IPR022775 AP complex, mu/sigma subunitDomainDomain
IPR028565 Mu homology domainDomainDomain
IPR036168 AP-2 complex subunit mu, C-terminal superfamilyFamilyHomologous superfamily
IPR043512 Mu2, C-terminal domainDomainDomain
IPR043532 AP-2 complex subunit mu, N-terminalDomainDomain

Diseases

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