Entity Details

Primary name MCM2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP97310
EntryNameMCM2_MOUSE
FullNameDNA replication licensing factor MCM2
TaxID10090
Evidenceevidence at protein level
Length904
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesMcm2

GO terms

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GOName
GO:0000727 double-strand break repair via break-induced replication
GO:0000785 chromatin
GO:0003678 DNA helicase activity
GO:0003688 DNA replication origin binding
GO:0003697 single-stranded DNA binding
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005664 nuclear origin of replication recognition complex
GO:0005737 cytoplasm
GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication
GO:0006268 DNA unwinding involved in DNA replication
GO:0006270 DNA replication initiation
GO:0006334 nucleosome assembly
GO:0006915 apoptotic process
GO:0016787 hydrolase activity
GO:0019899 enzyme binding
GO:0042393 histone binding
GO:0042555 MCM complex
GO:0046872 metal ion binding
GO:0071162 CMG complex
GO:0071353 cellular response to interleukin-4
GO:0090102 cochlea development
GO:1902975 mitotic DNA replication initiation
GO:1905775 negative regulation of DNA helicase activity

Subcellular Location

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Subcellular Location
Chromosome
Nucleus

Domains

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DomainNameCategoryType
IPR001208 MCM domainDomainDomain
IPR008045 DNA replication licensing factor Mcm2FamilyFamily
IPR012340 Nucleic acid-binding, OB-foldFamilyHomologous superfamily
IPR018525 Mini-chromosome maintenance, conserved siteSiteConserved site
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR027925 MCM N-terminal domainDomainDomain
IPR031327 Mini-chromosome maintenance proteinFamilyFamily
IPR033762 MCM OB domainDomainDomain
IPR041562 MCM, AAA-lid domainDomainDomain

Diseases

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