Entity Details

Primary name DAB1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP97318
EntryNameDAB1_MOUSE
FullNameDisabled homolog 1
TaxID10090
Evidenceevidence at protein level
Length588
SequenceStatuscomplete
DateCreated2002-02-11
DateModified2021-06-02

Ontological Relatives

GenesDab1

GO terms

Show/Hide Table
GOName
GO:0001764 neuron migration
GO:0005543 phospholipid binding
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005903 brush border
GO:0007162 negative regulation of cell adhesion
GO:0007264 small GTPase mediated signal transduction
GO:0007399 nervous system development
GO:0007417 central nervous system development
GO:0007494 midgut development
GO:0007628 adult walking behavior
GO:0014069 postsynaptic density
GO:0016020 membrane
GO:0016358 dendrite development
GO:0021517 ventral spinal cord development
GO:0021589 cerebellum structural organization
GO:0021766 hippocampus development
GO:0021795 cerebral cortex cell migration
GO:0021799 cerebral cortex radially oriented cell migration
GO:0021813 cell-cell adhesion involved in neuronal-glial interactions involved in cerebral cortex radial glia guided migration
GO:0021942 radial glia guided migration of Purkinje cell
GO:0035556 intracellular signal transduction
GO:0042169 SH2 domain binding
GO:0042493 response to drug
GO:0043005 neuron projection
GO:0043025 neuronal cell body
GO:0043231 intracellular membrane-bounded organelle
GO:0043548 phosphatidylinositol 3-kinase binding
GO:0045177 apical part of cell
GO:0045666 positive regulation of neuron differentiation
GO:0045860 positive regulation of protein kinase activity
GO:0046426 negative regulation of receptor signaling pathway via JAK-STAT
GO:0048471 perinuclear region of cytoplasm
GO:0048712 negative regulation of astrocyte differentiation
GO:0050771 negative regulation of axonogenesis
GO:0051645 Golgi localization
GO:0097477 lateral motor column neuron migration

Subcellular Location

Show/Hide Table

Domains

Show/Hide Table
DomainNameCategoryType
IPR006020 PTB/PI domainDomainDomain
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily

Diseases

Show/Hide Table

Interactions

41 interactions

InteractorPartnerSourcesPublicationsLink
DAB1_MOUSEA4_MOUSEIntAct, MINT, UniProt10460257 11517249 12826668 details
DAB1_MOUSEITB7_HUMANMINT12606711 details
DAB1_MOUSEITB5_HUMANMINT12606711 details
DAB1_MOUSEITB3_HUMANMINT12606711 details
DAB1_MOUSEITB1_HUMANMINT12606711 details
DAB1_MOUSEITB2_HUMANMINT12606711 details
DAB1_MOUSELRP2_MOUSEIntAct10827173 details
DAB1_MOUSELRP1_MOUSEIntAct10827173 details
DAB1_MOUSELRP8_MOUSEIntAct10827173 details
DAB1_MOUSELDLR_MOUSEBioGRID, IntAct10380922 10827173 details
DAB1_MOUSEVLDLR_MOUSEBioGRID, IntAct10380922 10827173 15249135 details
DAB1_MOUSEAPLP1_MOUSEIntAct, UniProt10460257 12826668 details
DAB1_MOUSESIA1A_MOUSEIntAct12646221 details
DAB1_MOUSECRKL_MOUSEBioGRID, MINT15062102 15110774 15316068 details
DAB1_MOUSEDAB2P_MOUSEBioGRID, UniProt12877983 details
DAB1_MOUSEWASP_MOUSEBioGRID15361067 details
DAB1_MOUSECRK_MOUSEBioGRID15062102 15316068 details
DAB1_MOUSEMK14_MOUSEBioGRID15110774 details
DAB1_MOUSECDK6_MOUSEBioGRID15110774 details
DAB1_MOUSECDK5_MOUSEBioGRID12077184 16529723 details
DAB1_MOUSEDOCK1_MOUSEBioGRID15316068 details
DAB1_MOUSEFYN_MOUSEBioGRID16529723 details
DAB1_MOUSEPCD18_MOUSEIntAct11716507 details
DAB1_MOUSEAPLP2_MOUSEIntAct10460257 details
DAB1_MOUSEMYO6_HUMANUniProt11967127 details
DAB1_MOUSESH3K1_HUMANUniProt14596919 details
DAB1_MOUSEEFNB3_HUMANDIP21460838 details
DAB1_MOUSEEFNB2_MOUSEBioGRID, DIP21460838 details
DAB1_MOUSECUL5_MOUSEBioGRID17974915 details
DAB1_MOUSEPLCG1_MOUSEBioGRID15062102 details
DAB1_MOUSESRC_MOUSEBioGRID15062102 details
DAB1_MOUSEYES_MOUSEBioGRID15062102 details
DAB1_MOUSEPTN11_MOUSEBioGRID15062102 details
DAB1_MOUSENOTC1_MOUSEBioGRID19571148 details
DAB1_MOUSENCK1_MOUSEBioGRID15110774 details
DAB1_MOUSENCK2_MOUSEBioGRID15110774 details
DAB1_MOUSEACTB_MOUSEBioGRID15110774 details
DAB1_MOUSEVLDLR_HUMANBioGRID15718228 details
DAB1_MOUSEEFNB3_MOUSEBioGRID21460838 details
DAB1_MOUSEEFNB1_MOUSEBioGRID21460838 details
DAB1_MOUSEA4_HUMANBioGRID16458391 details