Entity Details

Primary name NRP1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP97333
EntryNameNRP1_MOUSE
FullNameNeuropilin-1
TaxID10090
Evidenceevidence at protein level
Length923
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesNrp1

GO terms

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GOName
GO:0001525 angiogenesis
GO:0001569 branching involved in blood vessel morphogenesis
GO:0001764 neuron migration
GO:0002040 sprouting angiogenesis
GO:0002042 cell migration involved in sprouting angiogenesis
GO:0003148 outflow tract septum morphogenesis
GO:0005021 vascular endothelial growth factor-activated receptor activity
GO:0005096 GTPase activator activity
GO:0005769 early endosome
GO:0005829 cytosol
GO:0005883 neurofilament
GO:0005886 plasma membrane
GO:0005925 focal adhesion
GO:0006930 substrate-dependent cell migration, cell extension
GO:0007229 integrin-mediated signaling pathway
GO:0007411 axon guidance
GO:0007413 axonal fasciculation
GO:0007507 heart development
GO:0008045 motor neuron axon guidance
GO:0008201 heparin binding
GO:0009611 response to wounding
GO:0009986 cell surface
GO:0010595 positive regulation of endothelial cell migration
GO:0016358 dendrite development
GO:0016477 cell migration
GO:0017154 semaphorin receptor activity
GO:0019838 growth factor binding
GO:0019901 protein kinase binding
GO:0021612 facial nerve structural organization
GO:0021636 trigeminal nerve morphogenesis
GO:0021637 trigeminal nerve structural organization
GO:0021649 vestibulocochlear nerve structural organization
GO:0021675 nerve development
GO:0021785 branchiomotor neuron axon guidance
GO:0021828 gonadotrophin-releasing hormone neuronal migration to the hypothalamus
GO:0030424 axon
GO:0030426 growth cone
GO:0030517 negative regulation of axon extension
GO:0031290 retinal ganglion cell axon guidance
GO:0031532 actin cytoskeleton reorganization
GO:0031966 mitochondrial membrane
GO:0032489 regulation of Cdc42 protein signal transduction
GO:0034446 substrate adhesion-dependent cell spreading
GO:0035729 cellular response to hepatocyte growth factor stimulus
GO:0035767 endothelial cell chemotaxis
GO:0035924 cellular response to vascular endothelial growth factor stimulus
GO:0036486 ventral trunk neural crest cell migration
GO:0038085 vascular endothelial growth factor binding
GO:0038189 neuropilin signaling pathway
GO:0038190 VEGF-activated neuropilin signaling pathway
GO:0042327 positive regulation of phosphorylation
GO:0043005 neuron projection
GO:0043025 neuronal cell body
GO:0043524 negative regulation of neuron apoptotic process
GO:0043542 endothelial cell migration
GO:0045766 positive regulation of angiogenesis
GO:0046718 viral entry into host cell
GO:0046872 metal ion binding
GO:0048008 platelet-derived growth factor receptor signaling pathway
GO:0048010 vascular endothelial growth factor receptor signaling pathway
GO:0048012 hepatocyte growth factor receptor signaling pathway
GO:0048485 sympathetic nervous system development
GO:0048666 neuron development
GO:0048841 regulation of axon extension involved in axon guidance
GO:0048842 positive regulation of axon extension involved in axon guidance
GO:0048843 negative regulation of axon extension involved in axon guidance
GO:0048844 artery morphogenesis
GO:0048846 axon extension involved in axon guidance
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
GO:0050918 positive chemotaxis
GO:0051491 positive regulation of filopodium assembly
GO:0051496 positive regulation of stress fiber assembly
GO:0051894 positive regulation of focal adhesion assembly
GO:0060385 axonogenesis involved in innervation
GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching
GO:0060978 angiogenesis involved in coronary vascular morphogenesis
GO:0060980 cell migration involved in coronary vasculogenesis
GO:0060982 coronary artery morphogenesis
GO:0061299 retina vasculature morphogenesis in camera-type eye
GO:0061441 renal artery morphogenesis
GO:0061549 sympathetic ganglion development
GO:0061551 trigeminal ganglion development
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0071526 semaphorin-plexin signaling pathway
GO:0071679 commissural neuron axon guidance
GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis
GO:0090259 regulation of retinal ganglion cell axon guidance
GO:0097374 sensory neuron axon guidance
GO:0097443 sorting endosome
GO:0097475 motor neuron migration
GO:0097490 sympathetic neuron projection extension
GO:0097491 sympathetic neuron projection guidance
GO:0098978 glutamatergic synapse
GO:0099055 integral component of postsynaptic membrane
GO:0099173 postsynapse organization
GO:0150018 basal dendrite development
GO:0150020 basal dendrite arborization
GO:1900026 positive regulation of substrate adhesion-dependent cell spreading
GO:1901166 neural crest cell migration involved in autonomic nervous system development
GO:1901998 toxin transport
GO:1902285 semaphorin-plexin signaling pathway involved in neuron projection guidance
GO:1902287 semaphorin-plexin signaling pathway involved in axon guidance
GO:1902336 positive regulation of retinal ganglion cell axon guidance
GO:1902378 VEGF-activated neuropilin signaling pathway involved in axon guidance
GO:1902946 protein localization to early endosome
GO:1903375 facioacoustic ganglion development
GO:1904835 dorsal root ganglion morphogenesis
GO:1905040 otic placode development
GO:2000251 positive regulation of actin cytoskeleton reorganization
GO:2001237 negative regulation of extrinsic apoptotic signaling pathway

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasm
Mitochondrion membrane

Domains

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DomainNameCategoryType
IPR000421 Coagulation factor 5/8 C-terminal domainDomainDomain
IPR000859 CUB domainDomainDomain
IPR000998 MAM domainDomainDomain
IPR008979 Galactose-binding-like domain superfamilyFamilyHomologous superfamily
IPR013320 Concanavalin A-like lectin/glucanase domain superfamilyFamilyHomologous superfamily
IPR014648 NeuropilinFamilyFamily
IPR022579 Neuropilin, C-terminalDomainDomain
IPR027146 Neuropilin-1FamilyFamily
IPR035914 Spermadhesin, CUB domain superfamilyFamilyHomologous superfamily

Diseases

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