Entity Details

Primary name CAC1A_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP97445
EntryNameCAC1A_MOUSE
FullNameVoltage-dependent P/Q-type calcium channel subunit alpha-1A
TaxID10090
Evidenceevidence at protein level
Length2368
SequenceStatuscomplete
DateCreated1999-07-15
DateModified2021-06-02

Ontological Relatives

GenesCacna1a

GO terms

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GOName
GO:0001505 regulation of neurotransmitter levels
GO:0005245 voltage-gated calcium channel activity
GO:0005516 calmodulin binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0005891 voltage-gated calcium channel complex
GO:0006816 calcium ion transport
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0007214 gamma-aminobutyric acid signaling pathway
GO:0007268 chemical synaptic transmission
GO:0007270 neuron-neuron synaptic transmission
GO:0007274 neuromuscular synaptic transmission
GO:0007416 synapse assembly
GO:0007628 adult walking behavior
GO:0008219 cell death
GO:0008331 high voltage-gated calcium channel activity
GO:0010817 regulation of hormone levels
GO:0014051 gamma-aminobutyric acid secretion
GO:0014056 regulation of acetylcholine secretion, neurotransmission
GO:0017156 calcium-ion regulated exocytosis
GO:0017158 regulation of calcium ion-dependent exocytosis
GO:0019226 transmission of nerve impulse
GO:0019233 sensory perception of pain
GO:0019905 syntaxin binding
GO:0021522 spinal cord motor neuron differentiation
GO:0021590 cerebellum maturation
GO:0021679 cerebellar molecular layer development
GO:0021680 cerebellar Purkinje cell layer development
GO:0021702 cerebellar Purkinje cell differentiation
GO:0021750 vestibular nucleus development
GO:0021953 central nervous system neuron differentiation
GO:0030425 dendrite
GO:0030644 cellular chloride ion homeostasis
GO:0031335 regulation of sulfur amino acid metabolic process
GO:0032353 negative regulation of hormone biosynthetic process
GO:0032991 protein-containing complex
GO:0035249 synaptic transmission, glutamatergic
GO:0042391 regulation of membrane potential
GO:0042593 glucose homeostasis
GO:0042995 cell projection
GO:0043025 neuronal cell body
GO:0043113 receptor clustering
GO:0043204 perikaryon
GO:0043524 negative regulation of neuron apoptotic process
GO:0046872 metal ion binding
GO:0048265 response to pain
GO:0048266 behavioral response to pain
GO:0048791 calcium ion-regulated exocytosis of neurotransmitter
GO:0048813 dendrite morphogenesis
GO:0050770 regulation of axonogenesis
GO:0050804 modulation of chemical synaptic transmission
GO:0050877 nervous system process
GO:0050883 musculoskeletal movement, spinal reflex action
GO:0050885 neuromuscular process controlling balance
GO:0050905 neuromuscular process
GO:0051899 membrane depolarization
GO:0060024 rhythmic synaptic transmission
GO:0070509 calcium ion import
GO:0070588 calcium ion transmembrane transport
GO:0098978 glutamatergic synapse
GO:0099059 integral component of presynaptic active zone membrane
GO:0099626 voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels
GO:1901385 regulation of voltage-gated calcium channel activity
GO:1904645 response to amyloid-beta
GO:1904646 cellular response to amyloid-beta

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR002077 Voltage-dependent calcium channel, alpha-1 subunitFamilyFamily
IPR005448 Voltage-dependent calcium channel, P/Q-type, alpha-1 AFamilyFamily
IPR005821 Ion transport domainDomainDomain
IPR014873 Voltage-dependent calcium channel, alpha-1 subunit, IQ domainDomainDomain
IPR027359 Voltage-dependent channel domain superfamilyFamilyHomologous superfamily
IPR031649 Voltage-dependent L-type calcium channel, IQ-associated domainDomainDomain

Diseases

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